Ibrance 125mg 25’s Tablets (Palbociclib)
₨18,000.00
Ibrance 125mg is Pfizer’s palbociclib, a targeted CDK4/6 inhibitor for advanced breast cancer. It is available in Pakistan at onlinepharmacy.pk, imported through authorised channels.
Product Description
Brand: Ibrance
Packet Size: 25 tablets
Active ingredient: Palbociclib
Manufacturer: Pfizer
Treatment: Breast Cancer

✓ Medically reviewed by
Dr. Irfan Zia
Pharm.D · DRAP Reg. No. 1921245 · Reviewed March 2026
This product has been reviewed and approved by our DRAP-registered pharmacist for clinical accuracy. All medicines on onlinepharmacy.pk are authentic and sourced from licensed suppliers.
Additional Details
What is Ibrance used for?
Palbociclib is prescribed for hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer, in adults including men. It is always used together with endocrine therapy — an aromatase inhibitor such as letrozole as initial therapy, or fulvestrant after prior endocrine treatment — never on its own. It blocks CDK4 and CDK6, enzymes cancer cells rely on to divide, slowing tumour growth while endocrine therapy cuts the hormonal signal.
Dosage and how to take Ibrance
- One tablet daily for 21 days, then 7 days off — a 28-day cycle, repeated as your oncologist advises
- Swallow whole at about the same time daily; do not crush, chew or split
- If your pack contains capsules rather than film-coated tablets, take them with food — our pharmacist will confirm which presentation you received
- Avoid grapefruit and grapefruit juice throughout treatment
- Missed or vomited dose: skip it and take the next dose at the usual time — never double up
Monitoring and essential safety
Palbociclib lowers white blood cell counts in most patients. Expect a complete blood count before each cycle (and on Day 15 of the first two cycles); report fever, chills or infection signs immediately. Rare but serious lung inflammation (pneumonitis) can occur — urgent review for new breathlessness or cough. Ibrance can harm an unborn baby: effective contraception is required during and after treatment for both women and men. Common effects: fatigue, nausea, mouth sores, hair thinning, infections.
Storage
Store below 30°C in the original pack, out of reach of children. Return unused oncology medicines to a pharmacy for disposal.
Ibrance vs generic palbociclib in Pakistan
Generic palbociclib brands are marketed in Pakistan at lower prices. Ibrance is the Pfizer originator with the full global manufacturing record; approved generics can be legitimate alternatives when your oncologist agrees. We stock [list what you genuinely stock] and will quote both, with DRAP registration and batch details visible on every listing.
Why buy Ibrance from Online Pharmacy?
- DRAP-registered pharmacy — legally licensed to dispense prescription medicines
- Pharmacist prescription verification before every order
- Discreet plain packaging — no product details on the outer box
- Free pharmacist consultation by WhatsApp or phone
Medical disclaimer: Educational information only; it does not replace advice from your treating oncologist or pharmacist.
Recommended Dosage of Ibrance 125mg tablet?
The standard recommended dose of Ibrance 125mg is one tablet taken orally once daily for 21 consecutive days, followed by a 7-day break. This constitutes one complete 28-day cycle.
Warnings and Precautions
Serious Risks:
Interstitial Lung Disease (ILD)/Pneumonitis: This is a serious lung condition that can occur with Ibrance. Symptoms include shortness of breath, cough, and chest pain.
Low Blood Cell Counts: Ibrance can reduce the number of red blood cells, white blood cells, and platelets in your blood. This can increase the risk of infections, anemia, and bleeding.
Heart Problems: Some patients have experienced heart problems while taking Ibrance.
Liver Problems: Ibrance can affect your liver. Liver function tests will be monitored regularly.
Fetal Harm: Ibrance can harm an unborn baby. Women of childbearing age should use effective contraception.
Infertility: Ibrance may affect fertility in men.
Possible Side Effects of Ibrance 125mg Tablets
Ibrance, like most medications, can cause side effects. While not everyone experiences them, it’s important to be aware of the potential side effects.
Common Side Effects:
Fatigue: Feeling tired or weak.
Nausea: Feeling sick to your stomach.
Diarrhea: Loose or watery stools.
Low white blood cell count: This can increase the risk of infection.
Hair thinning or loss: This is temporary, and hair usually grows back.
Mouth sores: Painful sores in the mouth.
Serious Side Effects:
Heart problems: Such as irregular heartbeat or heart failure.
Lung problems: Like shortness of breath or cough.
Liver problems: Symptoms include yellowing of the skin or eyes.
Blood clots: Symptoms include pain, swelling, and redness in your legs.









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