Votrient 400 mg Tablets (Pazopanib)


(2 customer reviews)

Voltrient tablet contains (pazopanib) which is now available in Pakistan at Online Pharmacy. The price range of Voltrient 400mg Tablets is Rs 60,000/-. to Rs 69,000/-.

Product Description:

Brand: Voltrient
Packet Size: 30’s Tablets
Active ingredient: (pazopanib)
Manufacturer: Novartis
Treatment: Cancer

Additional Details

Additional Details

Uses of the Voltrient 400mg Tablets

It belongs to a class of drugs called tyrosine kinase inhibitors (TKIs). Here are the specific uses:

Advanced Renal Cell Carcinoma (RCC):
This is a type of kidney cancer. Votrient is used to treat patients with advanced RCC who have not received prior treatment.

Advanced Soft Tissue Sarcoma (STS):
This is a type of cancer that can develop in various tissues like muscles, fat, or blood vessels. Votrient is used to treat patients with advanced STS who have received prior chemotherapy and whose cancer has progressed.

How Does Voltrient Tablet Work?

Votrient works by targeting and blocking specific proteins called tyrosine kinases. These proteins play a crucial role in various cellular processes, including cell growth, division, and blood vessel formation. By blocking these proteins, Votrient can:

Starve tumors: It inhibits the development of new blood vessels within tumors, thereby limiting their blood supply and hindering their growth.

Slow cancer spread: It may interfere with the ability of cancer cells to migrate and form new tumors in other parts of the body.

How Should You Take Voltrient 400mg Tablets?

We recommend that you take these tablets on an empty stomach. It’s important to swallow the tablets whole without crushing them, as crushing can alter how your body absorbs the medication. If you happen to miss a dose and there’s less than 12 hours until your next scheduled dose, you should skip the missed dose and just continue with your regular dosing schedule.

You are advised to take a daily dose of 800 mg, which means taking four 200 mg tablets at once, by mouth.

For patients with moderate hepatic impairment (total bilirubin > 1.5 to 3 × ULN and any ALT value), the recommended dose is 200 mg once daily.

For patients taking strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin), the dose should be reduced to 400 mg once daily.

For patients unable to tolerate the initial dose reduction, the dose may be further reduced to 200 mg once daily, and if this is not tolerated, VOTRIENT should be permanently discontinued.

Warnings and Precautions of Voltrient 400mg Tablets

Warnings and Precautions of Voltrient 400mg Tablets

When taking Votrient tablets, it’s crucial for you to be aware of certain warnings and precautions to ensure your safety:


Do not take Votrient if you have severe liver disease. Pazopanib, the active ingredient, can lead to severe or even life-threatening liver issues. We’ll need to perform regular blood tests to monitor your liver function closely.
Immediately contact your doctor if you experience nausea, vomiting, pain in the upper stomach, loss of appetite, fatigue, easy bruising, dark-colored urine, or jaundice (a yellowing of your skin or eyes).

Votrient may reduce the blood cells that help your body fight infections and aid in clotting, increasing your risk of infections or making it easier for you to bleed. If you notice unusual bruising or bleeding, or if you have signs of an infection like fever, chills, or body aches, let your doctor know right away.


Ensure Votrient is safe for you by informing your doctor if you’ve had any of the following:

Liver, heart disease, heart rhythm issues, or long QT syndrome.
High blood pressure.
A history of blood clots or stroke.
Thyroid disorders.
Headaches, seizures, or vision problems.
Any perforation (hole or tear) or fistula (abnormal passageway) in your stomach or intestines.
Stomach or intestinal bleeding; or
Surgery in the last 7 days.
This straightforward guidance is designed to help you understand the precautions necessary for taking Votrient safely.

Possible Side Effects of Voltrient Tablets

Possible Side Effects of Voltrient Tablets

If you’re taking Votrient tablets, it’s important to be aware of possible side effects and know when to seek immediate medical attention:

If you experience symptoms of extremely high blood pressure, such as severe chest pain, intense headaches, blurred vision, pounding in your neck or ears, anxiety, difficulty breathing, or feelings of fainting, you should call your doctor or get emergency medical help right away.

Contact your doctor immediately if you have any of the following:

Headaches, confusion, changes in your mental state, vision problems, or seizures.
Sudden chest pain, wheezing, or a dry cough.
Unusual bleeding or bruising.
Any wound or surgical cut that doesn’t heal.
Rapid or pounding heartbeats, fluttering in your chest, or sudden dizziness, feeling like you might faint.
Symptoms of heart problems, including swelling, rapid weight gain, or shortness of breath.
Indications of liver issues, such as nausea, vomiting, pain in the upper stomach, lack of appetite, fatigue, dark urine, or jaundice.
Signs of infection, like fever, runny nose, sore throat, body aches, skin sores, or pain/burning during urination.
Evidence of stomach bleeding, including stomach pain or swelling, bloody or tarry stools, or coughing up blood or vomit that looks like coffee grounds.
Heart attack symptoms, such as chest pain or pressure, pain spreading to your jaw or shoulder, nausea, and sweating.
Signs of a stroke or blood clot, including sudden numbness or weakness, severe headache, slurred speech, vision problems, chest pain, sudden shortness of breath, or pain or a cold sensation in an arm or leg.
Symptoms of tumor cell breakdown, like fatigue, weakness, muscle cramps, nausea, vomiting, diarrhea, irregular heart rate, or tingling in your hands and feet or around your mouth.

Can We Use Other Medicines with Voltrient Tablets?

Yes, but it’s crucial to remember that Votrient (pazopanib) can interact with other medications. We strongly advise you to share a complete list of all the medications you’re currently taking with your healthcare provider. This list should include prescription drugs, over-the-counter medicines, vitamins, and herbal supplements. The reason is that Votrient and other medicines can influence each other, potentially leading to side effects.

Can You Take Voltrient Tablets if You’re Pregnant?

Votrient (pazopanib) could harm an unborn baby, so it’s advised not to use it during pregnancy. If you’re capable of becoming pregnant, we strongly recommend taking steps to prevent pregnancy while on Votrient, using reliable contraception methods. If you find out you’re pregnant while taking Votrient, it’s crucial to understand the potential risks to the fetus. Discussing the potential risks and benefits of Votrient treatment with your healthcare provider is especially important if you’re pregnant or breastfeeding.

Reviews (2)

2 reviews for Votrient 400 mg Tablets (Pazopanib)

  1. ajaz

    fast delivery and excellent packaging.

  2. Hasnain Ahmed

    knowledgeable customer support they helped with all questions

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