Ocrevus 300mg/10ml Injection (Ocrelizumab)


Ocrevus injection contains (Ocrelizumab) which is now available in Pakistan at Online Pharmacy. The price range of the Ocrevus injection is Rs. 450,000/- to Rs 520,000/-.

Product Description

Brand: Ocrevus
Form: Injection
Packet Size: 1 Vial
Active ingredient: Ocrelizumab
Manufacturer: Roche Pakistan Pvt Ltd
Treatment: Multiple Sclerosis

Additional Details

Additional Details

Uses of the Ocrevus 300mg Injection

Ocrevus (ocrelizumab) 300mg injection is a prescription medication used to treat certain relapsing forms of multiple sclerosis (MS) in adults. Here’s a breakdown of the specific conditions Ocrevus can target:

Relapsing-Remitting MS (RRMS): This is the most common type of Multiple Sclerosis, characterized by periods of relapse (worsening symptoms) followed by periods of remission (reduced or no symptoms). Ocrevus can help reduce the frequency and severity of relapses.

Active Secondary Progressive MS (SPMS): In this form of Multiple Sclerosis, there’s a gradual worsening of symptoms over time, with occasional relapses. Ocrevus can help slow down disease progression and reduce the frequency of relapses.

Clinically Isolated Syndrome (CIS): This is a first-time episode of neurological symptoms that may indicate a high risk of developing Multiple Sclerosis in the future. Ocrevus can be used in some cases to delay the conversion to clinically definite Multiple Sclerosis.

How Does Ocrevus Injection Work?

Ocrevus works by targeting a specific type of immune cell called a B-lymphocyte. B-lymphocytes are involved in the immune system’s response, but in Multiple Sclerosis, they can mistakenly attack the protective sheath around nerve cells in the brain and spinal cord. Ocrevus depletes these B-cells, potentially helping to reduce inflammation and slow down the progression of Multiple Sclerosis.

How Should You Take Ocrevus 300mg Injection?

Ocrevus is not for self-administration. It’s a prescription medication given as an intravenous (IV) infusion by a qualified healthcare professional in a healthcare setting.

Dosage and Schedule: The standard treatment regimen involves two initial doses of Ocrevus 300mg each, given two weeks apart. This is followed by subsequent single doses of Ocrevus 600mg administered every 6 months.

Preparation and Infusion: A healthcare professional will prepare the Ocrevus solution for infusion and administer it through an IV line inserted into a vein in your arm. The infusion process itself can take several hours.

The recommended dosage of Ocrevus (ocrelizumab) 300mg injection for relapsing forms of multiple sclerosis (MS) in adults is a two-part process:

Initial Dosing:

The initial treatment phase involves two separate Ocrevus 300mg infusions spaced two weeks apart.

This initial phase helps establish the medication’s presence in your body.

Maintenance Dosing:

Following the initial two doses, Ocrevus is typically administered as a single 600mg dose every 6 months.

This maintenance dosage helps sustain the medication’s effect in managing your Multiple Sclerosis.

Warnings and Precautions

Warnings and Precautions

Ocrevus 300mg Injection comes with several warnings and precautions that you should be aware of before starting treatment.


Increased Risk of Infections: Ocrevus weakens your immune system by reducing B-cells, which can increase your susceptibility to infections, including serious or potentially life-threatening ones.

Inform your doctor immediately if you experience any signs of infection, such as fever, chills, cough, or urinary tract symptoms.

It’s crucial to maintain good hygiene practices and discuss any vaccinations you may need with your doctor before starting Ocrevus treatment.

Brain Infection (PML): A rare but severe side effect is a brain infection called progressive multifocal leukoencephalopathy (PML). PML can cause serious neurological problems. Your doctor will assess your risk factors for PML before starting Ocrevus.


Allergic Reactions: Ocrevus can cause infusion reactions during or after the infusion. These reactions can range from mild (fever, chills, headache) to severe (allergic shock). Inform your doctor if you have any history of allergies, especially to proteins.

Hepatitis B Reactivation: If you have a history of hepatitis B infection, Ocrevus can increase the risk of the virus becoming active again. Your doctor will monitor you for this potential complication.

Certain Cancers: There’s limited information on the long-term effects of Ocrevus on cancer risk. Discuss any personal or family history of cancer with your doctor before starting Ocrevus.

Possible Side Effects of Ocrevus Injection

Possible Side Effects of Ocrevus Injection

Ocrevus 300mg Injection can cause a variety of side effects, some more common than others.

Common Side Effects:

Infusion Reactions: These can occur during or after the infusion and may include:

Muscle aches and pains

Upper Respiratory Tract Infections: Ocrevus can increase your susceptibility to infections like colds, sinus infections, or bronchitis.

Skin Infections: Skin infections such as shingles or urinary tract infections (UTIs) may also be more common.

Serious Side Effects:

Increased Risk of Infections: As mentioned previously, Ocrevus weakens the immune system, making you more prone to serious infections. Be aware of symptoms and inform your doctor promptly if you experience any signs of infection.

Brain Infection (PML): This is a rare but severe side effect. PML can cause serious neurological problems. Your doctor will assess your risk for PML before starting Ocrevus treatment.

Can We Use Other Medicines with Ocrevus Injection?

Ocrevus (ocrelizumab) 300mg injection can interact with other medications, potentially affecting their effectiveness or increasing the risk of side effects. Include other medications used to treat Multiple Sclerosis or medications used after organ transplants.

Certain medications can affect how your body processes Ocrevus, potentially altering its effectiveness. Examples include some antibiotics, antifungals, and medications that affect liver function.

Can Alcohol Drinker Take Ocrevus Injection?

Yes, Alcohol drinkers can take Ocrevus injections. Alcohol doesn’t typically interact with Ocrevus. But it’s always a good idea to have a chat with your doctor about how much alcohol is safe while you’re on Ocrevus treatment.

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