Lenvima 14mg Tablets (Lenvatinib)
₨45,000.00
Lenvima tablets contain (Lenvatinib) which is now available in Pakistan at Online Pharmacy. The price range of the Lenvima tablet is Rs. 41,000/- to Rs. 48,000/-.
Product Description
Brand: Lenvima
Form: Capsules
Active ingredient: Ramucirumab
Manufacturer: Eisai
Treatment: Thyroid cancer
Additional Details
Uses of the Lenvima 14mg Tablets
Lenvima (Lenvatinib) 14mg tablets are a prescription medication used to treat certain types of advanced cancers. Here’s a breakdown of the conditions Lenvima can be used for.
Differentiated Thyroid Cancer: If you have radioactive iodine-refractory differentiated thyroid cancer (a type of thyroid cancer that has not responded well to treatment with radioactive iodine), Lenvima might be used to slow or stop the growth of cancer cells.
Kidney Cancer (Renal Cell Carcinoma): In the first-line setting (initial treatment) for a specific type of advanced kidney cancer, Lenvima is used in combination with another medication called pembrolizumab (an immunotherapy medication).
Liver Cancer (Hepatocellular Carcinoma): When surgery or other curative options are not suitable for advanced liver cancer, Lenvima might be used as a first-line treatment.
How Does Lenvima Tablet Work?
Lenvima (Lenvatinib) 14mg tablets target specific proteins within cancer cells that play a crucial role in their growth and spread.
Targets Multiple Signaling Pathways: Lenvima doesn’t target just one protein, but rather several proteins involved in different signaling pathways within cancer cells. These pathways are like communication channels that tell cancer cells to grow, multiply, and form new blood vessels.
Blocks Signals for Growth and Spread: By inhibiting these proteins, Lenvima disrupts these signaling pathways. This can help to:
Slow down the growth of cancer cells.
Reduce the ability of cancer cells to spread to other parts of the body.
Potentially starve tumors by limiting the formation of new blood vessels that supply them with nutrients.
How Should You Take Lenvima 14mg Tablet?
Lenvima (Lenvatinib) 14mg tablets are a powerful medication, and it’s crucial to take them exactly as prescribed by your doctor. Here’s a breakdown of what you should know.
Dosage: Your doctor will determine the most appropriate dosage for you based on your specific condition, overall health, and response to treatment. They will provide clear instructions on the exact number of 14mg tablets you should take each day.
Swallowing the Tablets: Take Lenvima tablets whole. Do not crush, chew, or break them before swallowing.
With or Without Food: Lenvima can be taken with or without food. However, if you experience any stomach upset after taking it on an empty stomach, you can try taking it with food to see if it helps.
Recommended Dosage of Lenvima Tablet
The recommended dosage of Lenvima for differentiated thyroid cancer (DTC) is 24mg (two 10mg capsules and one 4mg capsule) orally once daily.
Warnings and Precautions
Lenvima (Lenvatinib) 14mg tablets come with several warnings and precautions that you should be aware of before starting treatment.
Increased Risk of Bleeding:
Lenvima can significantly increase your risk of bleeding, including severe and potentially fatal hemorrhages. This risk is even higher if you have certain medical conditions or are taking medications that also increase bleeding risk. Be extra careful to avoid injuries and inform your doctor immediately if you experience any bleeding.
Gastrointestinal (GI) Perforations:
Lenvima can increase the risk of holes forming in your stomach or intestines (perforations). This is a life-threatening complication. Symptoms of perforation can include severe abdominal pain, nausea, vomiting, and fever. If you experience any of these symptoms, seek medical attention immediately.
Impaired Wound Healing:
Lenvima can impair wound healing, so it’s important to inform your doctor about any upcoming surgeries before starting treatment. They may recommend delaying Lenvima treatment for a certain period to allow for proper wound healing after surgery.
Arterial Thromboembolic Events (ATEs):
Lenvima can increase the risk of ATEs, which are blood clots that can form in arteries and travel to various organs, potentially leading to strokes, heart attacks, or other serious issues. Be aware of symptoms like sudden weakness, chest pain, shortness of breath, or trouble speaking, which could indicate an ATE.
High Blood Pressure (Hypertension):
Lenvima can cause high blood pressure. Your doctor will monitor your blood pressure regularly and may prescribe medication to control it if necessary.
Proteinuria and Nephrotic Syndrome:
Excess protein in the urine (proteinuria) and a related kidney disorder (nephrotic syndrome) can occur with Lenvima use. Your doctor will monitor your kidney function through blood and urine tests.
Other Potential Warnings and Precautions:
Lenvima can worsen pre-existing liver problems.
It can cause a rare neurological condition called posterior reversible encephalopathy syndrome (PRES).
Thyroid function abnormalities can happen.
There’s a risk of embryo-fetal toxicity, meaning Lenvima can harm an unborn baby. Women who are pregnant or plan to become pregnant should not take Lenvima.
Lenvima can cause fetal malformations in a developing baby if the father is taking it. Men taking Lenvima should use effective contraception and avoid fathering a child during treatment.
Possible Side Effects of Lenvima 14mg Tablets
Lenvima 14mg Tablets can cause a variety of side effects, some more common than others.
Common Side Effects:
High Blood Pressure (Hypertension): This is a common side effect of Lenvima. Your doctor will monitor your blood pressure regularly and may prescribe medication to control it if needed.
Fatigue: Feeling tired or weak is a common side effect of Lenvima.
Diarrhea: Lenvima can cause diarrhea in some patients. Your doctor can recommend medications or dietary changes to manage it.
Nausea and Vomiting: These are gastrointestinal side effects that may occur with Lenvima. There are medications that can help manage these symptoms.
Headache: Headaches can occur with Lenvima use.
Decreased Appetite: Loss of appetite is a possible side effect.
Skin Rash: Lenvima can cause a rash on your hands, feet, or elsewhere on your body. Inform your doctor if you develop any rashes.
Mouth Soreness: Mouth sores or inflammation can occur while taking Lenvima.
Serious Side Effects:
Increased Risk of Bleeding: Lenvima can significantly raise your risk of bleeding, including severe or potentially fatal hemorrhages. Be extra careful to avoid injuries and inform your doctor immediately if you experience any bleeding.
Gastrointestinal (GI) Perforations: Lenvima can increase the risk of holes forming in your stomach or intestines (perforations). This is a life-threatening complication. If you experience severe stomach pain, inform your doctor right away.
Impaired Wound Healing: Lenvima can impair wound healing. Inform your doctor about any upcoming surgeries before starting treatment. They may recommend delaying Lenvima for a certain period.
Arterial Thromboembolic Events (ATEs): Lenvima can increase the risk of blood clots that can form in arteries and travel to various organs, potentially leading to strokes, heart attacks, or other serious issues.
Proteinuria and Nephrotic Syndrome: Excess protein in the urine and a related kidney disorder can occur with Lenvima use. Your doctor will monitor your kidney function regularly.
Thyroid Function Abnormalities: Lenvima can affect your thyroid function. Your doctor will check your thyroid hormone levels regularly.
Can We Use Other Medicines with Lenvima Tablet?
Lenvima can interact with other medications, potentially increasing the risk of side effects or reducing its effectiveness.
It’s crucial to discuss all medications you take (prescription, over-the-counter, vitamins, herbal supplements) with your doctor before starting Lenvima treatment. This allows your doctor to assess potential interactions and create a safe and effective treatment plan.
Can Alcohol Drinker Take Lenvima Tablet?
No, it’s generally not recommended for alcohol drinkers to take Lenvima (Lenvatinib) 14mg tablets
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