Actilyse 50mg Injection (Alteplase)
₨45,000.00
Actilyse 50mg injection contains alteplase — a recombinant tissue plasminogen activator (rt-PA) manufactured by Boehringer Ingelheim, one of the world’s leading pharmaceutical companies. Actilyse is a thrombolytic medicine that dissolves blood clots by activating the body’s natural fibrinolytic system. It is used in hospital settings for the treatment of acute ischaemic stroke, massive pulmonary embolism, and ST-elevation myocardial infarction (STEMI). Online Pharmacy stocks original Boehringer Ingelheim Actilyse with cold-chain delivery maintained throughout dispatch across Pakistan.
Product Description
Brand: Actilyse
Packet Size: 1 Vial Injection
Active ingredient: alterplase
Manufacturer: Boehrnger Ingelheim
Treatment: Blood Clots
✓ Medically reviewed by
Dr. Irfan Zia
Pharm.D · DRAP Reg. No. 1921245 · Reviewed March 2026
This product has been reviewed and approved by our DRAP-registered pharmacist for clinical accuracy. All medicines on onlinepharmacy.pk are authentic and sourced from licensed suppliers.
Additional Details
What is Actilyse 50mg used for?
Actilyse 50mg has three principal licensed clinical indications:
- Acute ischaemic stroke: Alteplase is the only licensed thrombolytic for ischaemic stroke in Pakistan. It is administered intravenously within 4.5 hours of symptom onset to dissolve the clot blocking blood flow to the brain, reducing disability and improving neurological outcomes.
- Massive pulmonary embolism (PE): Used in life-threatening PE where haemodynamic compromise (low blood pressure, shock) is present and surgical intervention is not immediately available.
- ST-elevation myocardial infarction (STEMI): When primary percutaneous coronary intervention (PCI) is not available within 120 minutes of diagnosis, Actilyse is used to restore coronary artery blood flow.
All three indications require hospital-based administration under the supervision of a specialist physician. Actilyse is not for home use.
How Does Actilyse 50mg Injection Work?
Actilyse 50mg injection is a very powerful medicine that dissolves your blood clots and breaks down the fibrin, which is a protein that creates your clot formation. Actilyse easily dissolves the clot from the blood and eases the normal blood flow to the affected areas.
How Should You Take Actilyse 50mg Injection?
You should take Actilyse 50mg injection into a vein under the supervision of a professional healthcare.
Preparation: The medicine is first mixed with a powder and sterile water to form a solution.
Administration: Then the solution is inserted through a drip into a vein.
Storage and cold-chain requirements
Cold-chain essential: Actilyse 50mg must be stored at 2°C to 8°C. Do not freeze. Protect from light. Online Pharmacy dispatches all Actilyse orders in validated temperature-controlled cold-chain packaging with gel ice packs and insulating liners to maintain 2–8°C throughout delivery.
- Store at 2–8°C (refrigerator temperature) — do not freeze
- Once reconstituted, use within 8 hours if stored at 2–8°C
- Keep in original carton to protect from light
- Discard any unused solution — do not store reconstituted product
Why source Actilyse from Online Pharmacy?
- Original Boehringer Ingelheim product — batch-verifiable and traceable
- Cold-chain delivery nationwide — validated temperature-controlled packaging throughout transit
- DRAP-registered pharmacy with pharmacist prescription verification
- Institutional and hospital procurement available — contact us for volume orders
- Nationwide delivery: Karachi (same day), Lahore/Islamabad (1–2 days), other cities (2–4 days)
Medical disclaimer: This information is for educational and procurement reference only. Actilyse is a hospital-administered medicine. It must be prescribed by a registered specialist and administered in a clinical setting with appropriate monitoring. For emergencies call 1122 or proceed to the nearest hospital immediately.
Recommended Dosage of Actilyse 50mg Injection?
Acute Myocardial Infarction (Heart Attack): Typically, a total dose of 100mg is administered over 90 or 180 minutes.
Acute Massive Pulmonary Embolism (PE): The usual dose is also 100mg, administered over 120 minutes.
Acute Ischemic Stroke: The recommended dose is 0.9mg/kg body weight (maximum of 90mg) given over 60 minutes.
For more information, be sure to visit Online Pharmacy or talk to your doctor for further guidelines.
Warnings and Precautions
Actilyse 50mg injection carries many risks due to its ability to dissolve blood clots, so it’s very important to talk with your doctor. You should be aware of the following warnings and precautions.
Increased Risk of Bleeding
The most significant risk associated with Actilyse is bleeding that can further occur at the injection site, internally, or in the brain.
Conditions that give you a bleeding risk (e.g., recent surgery, head injury, uncontrolled high blood pressure) are contraindications for Actilyse use.
Other Precautions
Allergic Reactions: Like any medication, allergic reactions can happen to you.
Monitoring: You should check your blood pressure, heart rate, and other medical check-ups, which are really important during and after treatment.
Specific Conditions: Certain medical conditions (e.g., severe liver disease, active internal bleeding) may preclude the use of Actilyse.
Actilyse 50mg Injection can give you some side effects which can be serious so it’s very important that you should be aware of these potential side effects.
Possible Side Effects of Actilyse 50mg Injection
Common Side Effects:
Bleeding at the injection site
Nausea
Vomiting
Fever
Headache
Serious Side Effects:
Major Bleeding: This is the most significant risk and can occur in the brain, stomach, or other organs.
Allergic Reactions: These can range from mild to severe and may include rash, itching, swelling, or difficulty breathing.
Pharmacist Nabeel Rehman –
Our hospital has been sourcing Actilyse from Online Pharmacy for a few months now. The product is consistently original Boehringer Ingelheim, sealed correctly, and arrives with cold-chain packaging in good condition. Batch numbers are verifiable. The ordering process is straightforward and the pharmacist confirms details before dispatch.
Dr. Imrana Qureshi –
Finding consistent supply of Actilyse in Pakistan used to be difficult. Online Pharmacy has resolved that for us — they stock it reliably and the product quality is exactly as expected. Original vials, intact seals, cold-chain compliant packaging, and proper documentation every time. Good professional service.
Tariq Javed –
Placed an order for Actilyse and it arrived the following day in Rawalpindi. Product was original Boehringer Ingelheim with intact cold-chain packaging. The pharmacist called to confirm the prescription and clinical details before processing which was appreciated. Professional approach to a specialised medicine.
Asma Shaheen –
Have ordered Actilyse from Online Pharmacy on three occasions. Quality and packaging are consistent each time — original product, cold-chain maintained, expiry well within date. The pharmacist is responsive and knowledgeable. It is reassuring to have a dependable source for a specialist medicine of this kind.
Sohail Akhtar –
Actilyse is not widely stocked in Pakistan and Online Pharmacy has been a reliable supplier. Verified Boehringer Ingelheim vials with matching batch certificates. Delivery is handled with appropriate care — temperature-controlled packaging and correct storage conditions maintained throughout. Recommended for institutions.