Xeloda 500mg 120’s Tablets (Capecitabine)


Xeloda 500mg Tablets contain Capecitabine which is now available in Pakistan at Online Pharmacy. The price range of Xeloda tablets is Rs. 22,000/- to Rs 27,000/-.

Product Description

Brand: Xeloda
Packet Size: 120 Capsules
Active ingredient: Capecitabine
Manufacturer: Roche
Treatment: Colon Cancer

Additional Details

Additional Details

Uses of the Xeloda 500mg Tablets

Xeloda 500mg tablets are a prescription medication used to treat several types of cancer. Here’s a closer look at its uses:

Combating Various Cancers: Xeloda is used to treat colon cancer, rectal cancer, breast cancer, stomach cancer, esophageal cancer, and pancreatic cancer.

Treatment Stages: It can be used in different treatment stages. In some cases, it may be used alone, while in others, it’s combined with other chemotherapy medications or radiation therapy.

Specific Uses:

For colon cancer, Xeloda might be used after surgery to reduce the risk of the cancer returning (adjuvant treatment).

In breast cancer, it may be used if other chemotherapy options haven’t been successful.

How Does Xeloda Tablet Work?

Xeloda (capecitabine) works by targeting cancer cells in a two-step process:

Activation: Xeloda itself is actually an inactive form of the medication. Once you take the tablet, enzymes, mainly in tumor tissues, convert it into its active form, 5-fluorouracil (5-FU). This conversion happens more readily in cancer cells because they have higher levels of these specific enzymes.

Disrupting DNA Synthesis: 5-FU acts as an imposter molecule. It closely resembles uracil, a building block of DNA, the genetic material in cells. Cancer cells incorporate 5-FU into their DNA instead of uracil. This disrupts the proper formation and function of DNA, hindering the cancer cells’ ability to grow and divide.

By disrupting DNA synthesis, Xeloda essentially halts the growth and spread of cancer cells.

How Should You Take Xeloda 500mg tablets?

Swallow the Xeloda tablets whole with a glass of water. Do not crush, chew, or break the tablets. Take the tablets within 30 minutes after a meal. Food can help reduce stomach upset, a common side effect of Xeloda.

The recommended dosage of Xeloda 500mg tablets varies significantly depending on several factors.

For Colorectal Cancer:

Adjuvant (add-on) treatment: 1,250 mg/m2 twice daily for 14 days, followed by 7 days off.

Around surgery: 825-1,250 mg/m2 twice daily.

Metastatic or inoperable: 1,250 mg/m2 twice daily for 14 days, followed by 7 days off.

For Breast Cancer:

Advanced or metastatic: 1,000-1,250 mg/m2 twice daily for 14 days, followed by 7 days off.

For Gastric, Esophageal, or Gastroesophageal Junction Cancer:

Unresectable or metastatic: 625-1,000 mg/m2 twice daily for 21 days of a 21-day cycle.

For Pancreatic Cancer:

830 mg/m2 twice daily for 21 days of a 28-day cycle, in combination with gemcitabine.

Warnings and Precautions

Warnings and Precautions

Xeloda (capecitabine) tablets are a powerful medication used to fight cancer. Before starting treatment, it’s vital to understand some important warnings and precautions:

Not for Everyone: Xeloda is not suitable for everyone. Inform your doctor about any pre-existing medical conditions you have, especially:

• Severe kidney problems
• Compromised immune system
• Uncontrolled diarrhea

Blood Thinners: If you’re taking blood-thinning medications like warfarin, discuss this with your doctor. Xeloda can increase the risk of bleeding.

Pregnancy and Breastfeeding: Xeloda can harm an unborn baby. Avoid pregnancy while taking it and for some time after. Discuss birth control options with your doctor. It’s also not recommended for breastfeeding mothers.

Fertility Concerns: Xeloda can affect fertility in both men and women. Talk to your doctor if you have concerns about future fertility.

Skin Care: Xeloda can cause hand-foot syndrome, leading to redness, swelling, and pain in the palms and soles. Tell your doctor if you experience these symptoms. They may recommend ways to manage them, such as wearing comfortable shoes and gloves.

Sun Sensitivity: Xeloda can increase your sensitivity to sunlight. Practice sun protection by wearing hats, sunglasses, and broad-spectrum sunscreen (SPF 30 or higher) when outdoors.

Possible Side Effects of Xeloda Tablets

Possible Side Effects of Xeloda Tablets

Xeloda is an effective medication in treating various cancers, but like most medications, it can cause side effects. Here’s a breakdown of some possible side effects you might experience:

Digestive Issues: Nausea, vomiting, diarrhea, and mouth sores are common side effects. Your doctor can prescribe medications to help manage these or recommend dietary changes to ease discomfort.

Fatigue: Xeloda can make you feel tired and weak. Getting enough sleep, staying hydrated, and engaging in gentle exercise (with your doctor’s approval) can help manage fatigue.

Skin Problems: Hand-foot syndrome is a potential side effect, causing redness, swelling, and pain on the palms of your hands and soles of your feet. Inform your doctor if you experience these symptoms. They can recommend ways to manage them.

Hair Loss: Some people experience hair loss while taking Xeloda. This is usually temporary, and hair grows back after treatment.

Serious Side Effects:

While less common, some side effects require immediate medical attention. If you experience any of the following, contact your doctor right away:

• Severe or persistent nausea, vomiting, or diarrhea
• Signs of infection, such as fever, chills, or sore throat
• Easy bruising or bleeding
• Mental or mood changes, such as depression or confusion
• Vision problems
• Severe pain in your hands or feet

Can We Use Other Medicines with Xeloda Tablets?

Taking Xeloda (capecitabine) tablets alongside other medications requires caution due to potential interactions. Here’s why careful management is crucial:

Interaction Risks: Certain medications can interact with Xeloda, affecting its effectiveness or increasing the risk of side effects.

Examples of Interacting Medications:

  • Blood thinners (warfarin) can increase bleeding risk.
  • Folic acid supplements can reduce Xeloda’s effectiveness.
  • Other chemotherapy medications may require dosage adjustments when combined with Xeloda.

Can Alcohol Drinker Take Xeloda 500mg Tablets?

It is recommended to avoid alcohol while taking Xeloda 500 mg tablets, as alcohol intake can increase the side effects of drowsiness and dizziness.

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