Ofev 150mg (Nintedanib) Capsules


(1 customer review)

Ofev contains Nintedanib which is now available in Pakistan at Online Pharmacy. The price range of Ofev 150mg capsules is Rs.200,000/- to Rs.250,000/-.

Product Description

Brand: Ofev
Packet Size: 60’s Capsules
Active ingredient: Nintednib
Manufacturer: Boehringer Ingelheim
Treatment: Lung Diseases (IPF)

Additional Details

Additional Details

Uses of the Ofev 150mg Capsules

Ofev 150mg capsules are indicated for the treatment of specific lung conditions involving fibrosis, a process where scar tissue builds up, making it difficult to breathe.

Primary Uses:

Idiopathic Pulmonary Fibrosis (IPF): Ofev is primarily used for adults with IPF, a chronic and progressive lung disease characterized by scarring in the lungs. It helps slow down the worsening of IPF and improve lung function.

Chronic Interstitial Lung Disease (ILD) with a Progressive Phenotype: Ofev is also approved for adults with other chronic progressive ILDs showing similar characteristics as IPF, where fibrosis is actively worsening lung function.

Off-Label Uses:

While not officially approved, Ofev is sometimes used off-label for other conditions with similar fibrotic processes, such as:

Systemic Sclerosis-associated Interstitial Lung Disease (SSc-ILD)
Dupuytren’s contracture

How Does Ofev Capsules Work?

Ofev capsules are designed to block certain substances involved in the pathways that cause scarring of the lungs, also known as pulmonary fibrosis. By doing so, Ofev helps to slow down the worsening of lung disease and preserve lung function. It is the first FDA-approved therapy to slow the rate of decline in lung function in adults with certain types of lung disease, such as idiopathic pulmonary fibrosis (IPF) and interstitial lung disease.

How Should You Take Ofev Capsules?

You should take Ofev capsules twice a day, every 12 hours, following the instructions on your prescription label and any medication guides or instruction sheets. Your doctor may occasionally adjust your dose. Before starting Ofev, your doctor will conduct blood tests to ensure there are no conditions that would make it unsafe for you to use this medication.

Always take Ofev with food and a full glass of water. It’s important to swallow the capsule whole without crushing, chewing, breaking, or opening it. To help keep the treatment effective, try to take your doses at regular intervals, ideally every 12 hours.

The recommended dosage of Ofev 150mg capsules is 150 mg taken orally twice daily, approximately 12 hours apart, with food.

Warnings and Precautions of Ofev Capsules

Warnings and Precautions of Ofev Capsules

When taking Ofev, you should be aware of certain warnings and precautions:


Ofev can harm an unborn baby, causing birth defects or even death. To prevent this, avoid getting pregnant while using Ofev and for at least 3 months after your last dose. Use effective birth control along with an extra barrier method, like a condom, diaphragm, cervical cap, or contraceptive sponge.


To ensure Ofev is safe for you, inform your doctor if you have a history of:
Liver disease.
Heart problems.
Blood clots.
Bleeding issues (either personally or in your family).
Surgery on your stomach or intestines.
Smoking habits.
Use of blood thinners, such as warfarin (Coumadin, Jantoven).
You might also need to take a pregnancy test before starting treatment with Ofev to confirm you’re not pregnant.

Remember, these precautions are in place to keep you safe while using Ofev, so it’s important to follow them and discuss any concerns with your healthcare provider.

Possible Side Effects of Opev Capsules

Possible Side Effects of Opev Capsules

When taking Ofev capsules, it’s important for you to be aware of possible side effects. If you experience any of the following, contact your doctor immediately:

Severe ongoing nausea, vomiting, or diarrhea.
Intense stomach pain, bloating, or tenderness.
Bleeding from your rectum or blood in your stools.
Easy bruising or bleeding, or any wound that won’t heal.
Fever, chills, cough with mucus, chest pain, or shortness of breath.
Symptoms of a heart attack, such as chest pain or pressure, pain spreading to your jaw or shoulder, nausea, and sweating.
Liver problems are indicated by upper right side stomach pain, loss of appetite, tiredness, dark urine, or jaundice (yellowing of the skin or eyes).
Signs of a stroke include sudden numbness or weakness (particularly on one side of the body), slurred speech, and problems with vision or balance.

Can We Use Other Medicines with Ofev Capsules?

Before taking any other medications with Ofev capsules, it’s essential to consult a doctor or pharmacist. Some medications may interact with Ofev, which can increase the risk of side effects or reduce the effectiveness of the medication. For example, concomitant use of P-gp and CYP3A4 inhibitors (e.g., erythromycin) with Ofev may increase exposure to nintedanib.

Other medications that may interact with Ofev include rifamycins, St. John’s wort, drugs used to treat seizures (such as carbamazepine, phenytoin), and others. It’s important to inform the doctor of all medications, supplements, and vitamins being taken before starting Ofev capsules.

Can I Take an Ofev 150mg Capsules Before Driving?

It is mentioned that Ofev may cause side effects such as nausea, which could affect your ability to drive. Therefore, it is advisable to assess how Ofev affects you individually before driving.

Can You Take Ofev 150mg Capsules If You’re Pregnant?

If you are pregnant or think you might be pregnant, it is crucial to stop taking Ofev immediately and tell your doctor as soon as possible. They can discuss alternative treatment options and monitor your pregnancy for any potential complications.

Pregnant women were excluded from clinical trials of Ofev due to safety concerns.

Studies in animals have shown that Ofev can cause birth defects, miscarriage, and other pregnancy complications.

The medication leaflet explicitly states that Ofev must not be used during pregnancy.

Reviews (1)

1 review for Ofev 150mg (Nintedanib) Capsules

  1. ubaid

    Affordable option for imported medicines.

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