Rhophylac Injection Anti D 300mcg Pre-Filled Syringe
₨12,000.00
Rhophylac contains Rho (D) Immune Globulin which is now available in Pakistan at Online Pharmacy. The price range of Rhophylac 300mcg is Rs 10,000/-. to Rs 15,000/-.
Product Description:
Brand: CSL Behring
Packet Size: 1’s Syringe
Active ingredient: Human anti-d immunoglobulin
Manufacturer: Behring/Hakimsons
Treatment: Prevent the mother’s immune system from developing antibodies during Pregnancy.
Additional Details of Rhophylac Anti D Injection
Uses of the Rhophylac Injection
Rhophylac injection Anti-D 300mcg use to overcome Rh incompatibility during pregnancy to overcome hemolytic disease of the newborn, and treat immune thrombocytopenic purpura (ITP). It works by overcoming the antibodies against Rh-positive blood cells in Rh-negative individuals.
Prevention of Rh Incompatibility During Pregnancy:
If you are Rh-negative and pregnant with an Rh-positive baby, Rhophylac injection actually overcomes Rh incompatibility.
Prevention of Hemolytic Disease of the Newborn:
Rhophylac injection is given after childbirth if you are Rh-negative and have given to Rh-positive baby. It overcomes the hemolytic disease of the newborn (HDN) its a condition where the mother’s antibodies attack the baby’s red blood cells which leads to jaundice or anemia.
Treatment of Immune Thrombocytopenic Purpura (ITP):
Rhophylac is also used to treat ITP, a condition where the immune system destroys platelets. The injection helps by preventing the body from attacking its own platelets, thus increasing platelet count and reducing bleeding risk.
How Does Rhophylac Injection Work?
Rhophylac Anti-D 300mcg Injection works by preventing the immune system from producing antibodies against Rh-positive blood cells in Rh-negative individuals, particularly during pregnancy or after childbirth, and helps treat conditions like immune thrombocytopenic purpura (ITP).
Prevents Antibody Formation
When you receive Rhophylac, the injection contains Rh immunoglobulin (Anti-D), which binds to any Rh-positive red blood cells that may have entered your bloodstream. This prevents your immune system from recognizing them as foreign invaders and developing antibodies against them.
Prevents Rh Incompatibility During Pregnancy
If you are Rh-negative and pregnant with an Rh-positive baby, your body may produce antibodies against the baby’s Rh-positive blood cells, which can be harmful in future pregnancies. Rhophylac is given during pregnancy to stop this from happening, ensuring that your body does not mount an immune response against your baby’s blood.
Prevents Hemolytic Disease of the Newborn
After childbirth, if you are Rh-negative and have given an Rh-positive baby then Rhophylac helps in overcoming hemolytic disease in the newborn. This condition occurs when your body attacks the baby’s red blood cells, that give many complications. Rhophylac injection helps to overcome Rh-positive cells that might have entered your bloodstream during the delivery process.
Treats Immune Thrombocytopenic Purpura (ITP)
In conditions like ITP, where the immune system destroys platelets, Rhophylac helps prevent your body from attacking its own platelets. By blocking your immune response, it increases your platelet count and overcomes the risk of bleeding.
How Should You Take Rhophylac 300mcg Injection?
You should take Rhophylac 300mcg injection as per your doctor’s permission through an intramuscular (IM) or intravenous (IV) injection. Your doctor will give you the dose guidance depending on your health condition.
Follow Your Doctor’s Instructions
It’s very important to talk with your doctor since your doctor will decide your dosage depending on your condition, such as pregnancy, after childbirth, or for the treatment of immune thrombocytopenic purpura (ITP).
Administration Method
Rhophylac 300mcg is usually given through an intramuscular (IM) injection, although it can also be administered via intravenous (IV) injection depending on your medical situation. A healthcare provider will administer the injection at the appropriate site in your body. The injection is typically administered in the upper arm or thigh.
Timing of the Injection
Rhophylac is often given during pregnancy (around the 28th week) and after delivery if you are Rh-negative and have delivered an Rh-positive baby. If you’re receiving it for conditions like ITP, the timing of the injections will depend on your doctor’s guidance, usually based on platelet count or other clinical factors.
Post-Injection Care
After the injection is given you may experience some mild soreness at the injection site, but this should go away on its own. If you feel any unusual reactions or any side effects make sure to talk with your doctor immediately.
Monitor for Effectiveness
It’s very important to take your doctor appointment to make sure that Rhophylac is working fine. Your doctor will regularly check up your health especially during pregnancy or post pregnancy to make sure that everything is working well.
Recommended Dosage of Rhophylac Anti D 300mcg Injection
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For Rh Incompatibility During Pregnancy:
The typical recommended dosage is 300mcg of Rhophylac (1 vial) administered intramuscularly (IM) or intravenously (IV) at 28 weeks of gestation if you are Rh-negative and carrying an Rh-positive baby. A follow-up dose of 300mcg is usually given within 72 hours after delivery if the baby is Rh-positive. -
After Miscarriage or Ectopic Pregnancy:
A 300mcg dose of Rhophylac should be given as soon as possible, ideally within 72 hours after a miscarriage or ectopic pregnancy, to prevent the formation of Rh antibodies. -
For Treatment of Immune Thrombocytopenic Purpura (ITP):
In the case of ITP, the dose and frequency of Rhophylac may vary based on the individual’s condition and response to treatment. Your doctor will determine the appropriate dosage based on your platelet count and overall health status.
Warnings and Precautions of Rhophylac Injection
Rhophylac Injection should be used with caution in individuals with allergies to human immunoglobulin, those with a history of anaphylactic reactions, and people with severe immune disorders. Always consult your doctor for proper guidance.
Warnings and Precautions of Rhophylac Injection:
Allergic Reactions
If you have a history of allergic reactions to human immunoglobulin, Rhophylac may not be suitable to you and can cause you Anaphylaxis. If you feel any symptoms like swelling, difficulty in breathing or rash. It’s very important to talk with your doctor as your doctor will monitor your overall allergy response.
Severe Immune Disorders
Rhophylac is made from the human blood plasma so you should use it with care as it could affect you with immune deficiencies or any disorders. If you have any history of immune system issues. It’s very important to let your doctor know before starting any treatment.
Hyperviscosity and Blood Clotting Disorders
Rhophylac should be used with care in individuals with blood clotting disorders or those prone to hyperviscosity (thickening of the blood). The injection may lead to increased viscosity, which can cause complications, especially in individuals with pre-existing blood clotting conditions.
Infection Risks
Although the risk is very low due to extensive screening, there’s still a potential risk of transmitting infections from blood-derived products. Rhophylac is tested for viral infections, but the transmission of rare infections cannot be completely excluded.
Pregnancy and Breastfeeding
Rhophylac is generally considered safe for use during pregnancy, particularly if you are Rh-negative and pregnant with an Rh-positive baby. However, as with all medications, it should only be used under the guidance of your healthcare provider. It is also considered safe for breastfeeding, but you should always discuss this with your doctor.
Possible Side Effects of Rhophylac Injection
The side effects of Rhophylac Anti-D injection are fever, chills, headache, and in rare cases, more serious effects like allergic reactions like hemolysis or low blood pressure.
Side Effects of Rhophylac Anti-D Injection:
Pain at the Injection Site
It’s very common to have a mild pain, redness or swelling at the injection site where the Rhophylac injection is given.
Fever and Chills
Some people may develop a mild fever or chills shortly after receiving the injection. These symptoms usually pass within a few hours, but if they persist or worsen, you should consult your healthcare provider.
Headache
A headache is another common symptom. This can be mild to moderate in intensity and typically resolves without any treatment. It’s very important to talk with your doctor if it occurs.
Allergic Reactions
Rhophylac can cause allergic reactions like rashes, swelling, or difficulty breathing. If you have any signs of an allergic reaction like swelling of the face, lips or throat, make sure to talk with your doctor as well.
Hemolysis (Destruction of Red Blood Cells)
Although rare, Rhophylac can lead to hemolysis, where red blood cells are destroyed. This can cause symptoms like fatigue, pallor, or dark-colored urine. If you notice any of these symptoms, contact your healthcare provider.
Low Blood Pressure (Hypotension)
A few individuals may experience a drop in blood pressure after the injection. Symptoms may include dizziness, lightheadedness, or fainting. If these occur, report them to your doctor immediately.
Other Rare Side Effects
In very rare instances, Rhophylac may cause more serious side effects, such as blood clots or kidney issues. These are extremely uncommon but should be monitored for during your treatment.
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