Furolin 100mg Tablets (Nitrofurantoin)
₨4,500.00
Furolin 100mg tablets contains nitrofurantoin which is now available in Pakistan at Online Pharmacy. The price range of the furolin tablets is Rs 3,000 to Rs 6,000/-.
Product Description
Brand: Furolin
Form: Tablets
Packet Size: 30 Tablets
Active ingredient: Nitrofurantoin
Manufacturer: IASIS pharma
Treatment: Urinary Tract Infections (UTIs)
Additional Details
Uses of the Furolin 100mg Tablets
Furolin 100mg Tablets (Nitrofurantoin) are primarily used for the treatment and prevention of urinary tract infections (UTIs) caused by susceptible strains of bacteria. Here’s a breakdown of their most accurate and specific uses:
Treatment of Acute Uncomplicated UTIs
Furolin is commonly prescribed to treat bladder infections (cystitis), especially in women.
It targets Escherichia coli, Enterococcus, and other bacteria commonly responsible for UTIs.
Prevention of Recurrent UTIs
It may be used prophylactically (long-term, low dose) in individuals who frequently suffer from urinary tract infections.
Post-Surgical UTI Prophylaxis
Sometimes used after urinary catheterization or urologic procedures to prevent infection.
How Does Furolin 100mg Tablets Work?
Activation inside bacterial cells:
After being absorbed and excreted into the urine, Nitrofurantoin enters bacterial cells in the urinary tract.
Inside these cells, bacterial enzymes called nitrofuran reductases convert Nitrofurantoin into highly reactive intermediates.
Damage to bacterial components:
These reactive forms of the drug then attack and damage bacterial DNA, ribosomal proteins, and cell wall synthesis pathways.
This leads to inhibition of protein synthesis, DNA damage, and disruption of other essential metabolic processes.
Bactericidal effect in urine:
The drug achieves bactericidal (bacteria-killing) concentrations only in the urine, making it highly effective for infections localized to the bladder and urinary tract.
How Should You Take Furolin 100mg Tablets?
The tablet should be taken with food or milk, as this significantly improves absorption and helps minimize stomach upset. The usual adult dosage is 100mg twice daily, but your specific dose and duration may vary based on your condition and medical history.
Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this may increase the risk of side effects like nausea or throat irritation. For best results, take the medication at evenly spaced intervals, such as every 12 hours if taken twice daily. It is crucial to complete the full course of treatment, even if symptoms improve before the medication is finished, to prevent the infection from returning or becoming resistant.
If you forget a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed one and continue with your regular schedule. Do not double the dose to catch up. Always follow your healthcare provider’s instructions carefully and inform them of any unusual symptoms or side effects during the course of treatment.
Recommended Dosage of Furolin 100mg Tablets
The recommended dosage of Furolin 100mg tablets (nitrofurantoin) for adults is as follows:
For treatment of urinary tract infections (UTIs):
Either 100mg slow-release capsules twice daily (every 12 hours) for 7 days, or
50mg standard tablets four times daily (every 6 hours) for 7 days.
For severe infections, 100mg standard tablets four times daily may be used.
For prevention of recurrent UTIs:
50mg to 100mg once daily at bedtime.
Important administration notes:
Take with food to improve absorption and reduce stomach upset.
Space doses evenly throughout the day (e.g., if four times daily, take morning, midday, late afternoon, and bedtime).
Complete the full course even if symptoms improve early to prevent recurrence.
Pediatric dosing:
Based on body weight, typically 5-7 mg/kg/day divided into four doses for treatment, and 1-2 mg/kg/day for prevention, but must be determined by a doctor.
Not recommended for infants under 1 month of age.
Renal considerations:
Contraindicated if creatinine clearance is below 60 mL/min.
Warnings and Precautions of Furolin 100mg Tablets
Allergic Reactions: Do not use if you have a known allergy to nitrofurantoin or any ingredients in the tablet. Severe allergic reactions can include rash, itching, swelling, difficulty breathing, or anaphylaxis, which requires immediate emergency care.
Kidney Function: Nitrofurantoin should not be used if you have significantly impaired kidney function (creatinine clearance less than 60 mL/min) because the drug may not be effective and could cause toxicity.
Liver Problems: Avoid use if you have a history of liver dysfunction or jaundice related to nitrofurantoin. Liver inflammation or injury is a possible serious side effect.
Pregnancy and Newborns: Do not take nitrofurantoin at term (38 weeks or later), during labor, or if you are a newborn under 1 month old due to risk of hemolytic anemia and other complications.
Pulmonary Toxicity: Nitrofurantoin may cause lung problems such as pneumonitis or pulmonary fibrosis. Seek medical advice if you develop cough, chest pain, difficulty breathing, or fever.
Peripheral Neuropathy: Risk of nerve damage causing numbness, tingling, or weakness, especially in patients with anemia, diabetes, vitamin B deficiency, or electrolyte imbalance. Discontinue if symptoms develop.
Other Precautions: Use caution in elderly patients and those with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to risk of hemolytic anemia. Monitor for signs of blood disorders, lupus-like syndrome, or severe diarrhea that could indicate superinfection or colitis.
Possible Side Effects of Furolin 100mg Tablets
Possible Side Effects of Furolin 100mg Tablets (Nitrofurantoin):
Common side effects:
Headache, dizziness, drowsiness
Gas, upset stomach, nausea, vomiting
Mild diarrhea
Rash, itching, vaginal itching or discharge
Muscle or joint pain
Temporary hair loss (rare)
Serious side effects (require immediate medical attention):
Allergic reactions: swelling of face, lips, tongue, or throat; difficulty breathing; hives; rash; itching
Lung problems: cough, chest pain, shortness of breath, fever, chills
Liver damage: yellowing of skin or eyes, dark urine, pale stools, itching, loss of appetite, stomach pain
Nerve damage (peripheral neuropathy): numbness, tingling, burning sensations in hands or feet, muscle weakness
Blood disorders: unexplained bruising or bleeding, sore throat, fever, feeling very tired or weak
Severe diarrhea: watery or bloody stools, stomach pain
Other: joint pain or swelling with fever, lupus-like symptoms, vision problems
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