Actilyse 50mg Injection (Alteplase)
₨32,000.00
Actilyse 50mg Injection contains alteplase, which is now available in Pakistan at Online Pharmacy. The price range of this is Rs.30,000/-. to Rs.35,000/-.
Product Description
Brand: Actilyse
Packet Size: 1 Vial Injection
Active ingredient: alterplase
Manufacturer: Boehrnger Ingelheim
Treatment: Blood Clots
Additional Details
Uses of the Actilyse 50mg Injection
Actilyse 50mg Injection (Alteplase) is a life-saving medication used to treat conditions caused by blood clots blocking blood vessels. Its primary uses include.
Acute myocardial infarction (heart attack): Dissolves blood clots blocking blood flow to the heart.
Acute massive pulmonary embolism (PE): Breaks down blood clots in the lungs, improving breathing and preventing complications.
Acute ischemic stroke: Dissolves blood clots in the brain, restoring blood flow and potentially reducing brain damage.
How Does Actilyse 50mg Injection Work?
Actilyse 50mg Injection (Alteplase) is a powerful medication that works by dissolving blood clots.
Clot breakdown: Actilyse breaks down the fibrin, a protein involved in clot formation.
Restored blood flow: By dissolving the clot, the medication helps restore normal blood flow to the affected area (heart, lungs, or brain).
Reduced tissue damage: This improved blood flow helps prevent tissue damage caused by the clot.
How Should You Take Actilyse 50mg Injection?
Actilyse 50mg Injection is administered intravenously (into a vein) by a healthcare professional. It’s a procedure that requires careful monitoring and expertise.
Preparation: The medication is prepared by mixing a powder with sterile water to form a solution.
Administration: The solution is then administered through a drip line into a vein.
Recommended Dosage of Actilyse 50mg Injection?
The dosage of Actilyse 50mg Injection varies depending on the specific condition being treated.
Acute myocardial infarction (heart attack): Typically, a total dose of 100mg is administered over 90 or 180 minutes.
Acute massive pulmonary embolism (PE): The usual dose is also 100mg, administered over 120 minutes.
Acute ischemic stroke: The recommended dose is 0.9mg/kg body weight (maximum of 90mg) given over 60 minutes.
Warnings and Precautions
Actilyse 50mg Injection carries significant risks due to its ability to dissolve blood clots. Therefore, it’s essential to be aware of the following warnings and precautions.
Increased Risk of Bleeding
The most significant risk associated with Actilyse is bleeding. It can occur at the injection site, internally, or in the brain.
Conditions that increase bleeding risk (e.g., recent surgery, head injury, uncontrolled high blood pressure) are contraindications for Actilyse use.
Other Precautions
Allergic reactions: Like any medication, allergic reactions can occur.
Monitoring: Close monitoring of blood pressure, heart rate, and other vital signs is essential during and after treatment.
Experienced healthcare professionals: Actilyse should only be administered by healthcare professionals experienced in its use and equipped to manage potential complications.
Specific conditions: Certain medical conditions (e.g., severe liver disease, active internal bleeding) may preclude the use of Actilyse.
Possible Side Effects of Actilyse 50mg Injection
Actilyse 50mg Injection can cause various side effects, some of which can be serious. It’s essential to be aware of these potential side effects:
Common Side Effects:
Bleeding at the injection site
Nausea
Vomiting
Fever
Headache
Serious Side Effects:
Major bleeding: This is the most significant risk and can occur in the brain, stomach, or other organs.
Allergic reactions: These can range from mild to severe and may include rash, itching, swelling, or difficulty breathing.
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