Tucaxen 150 mg Tablets (Tucatinib)

200,000.00

Tucaxen 150mg tablets contains Tucatinib, which is now available in Pakistan at Online Pharmacy. The price range of this is Rs.200,000/-. to Rs.220,000/-.

Product Description

Brand: Tucaxen
Packet Size: 30 tablets
Active ingredient: Tucatinib
Manufacturer: Evererst
Treatment: Breast Cancer

Category:
Additional Details

Additional Details

Uses of the Tucaxen 40mg Injection 

Breast Cancer Treatment: Tucaxen 150mg tablets are primarily used to treat locally advanced or metastatic HER2-positive breast cancer, especially in patients who have received at least one prior anti-HER2 treatment regimen. It is typically used in combination with trastuzumab and capecitabine. 

Inhibiting Cancer Cell Growth: Tucatinib, the active ingredient in Tucaxen, is a kinase inhibitor that blocks the activity of the HER2 and HER3 proteins involved in signaling pathways that promote cancer cell proliferation. By inhibiting these proteins, Tucaxen helps slow down or stop the progression of HER2-positive breast cancer cells. 

How Does Tucaxen 150mg Tablets Work? 

Tucaxen 150mg tablets, containing the active ingredient Tucatinib, work primarily as a targeted therapy for treating HER2-positive breast cancer. Here’s how it functions: 

Kinase Inhibition: Tucatinib is classified as a kinase inhibitor. It specifically targets and inhibits the activity of the HER2 and HER3 proteins, which are involved in signaling pathways that promote the growth and proliferation of cancer cells. By blocking these signals, Tucatinib helps to slow down or stop the growth of cancer cells that express the HER2 protein. 

Blocking Cancer Cell Growth: HER2-positive breast cancer cells often have mutations that lead to uncontrolled growth. Tucatinib interferes with the tyrosine kinase activity associated with the HER2 gene, preventing the phosphorylation process that is crucial for cancer cell signaling. This action leads to reduced tumor growth and may induce cancer cell death. 

How Should You Take Tucaxen 150mg Tablets? 

Here are the key points on how to take Tucaxen 150mg tablets: 

Swallow the tablets whole; do not chew, crush, or split them. 

Never consume a tablet that is broken, cracked, or otherwise non-intact. 

Take each dose at the same time daily, with or without a meal. 

If you vomit or miss a dose, take the next scheduled dose at its usual time. Do not double the next dose. 

Consult your doctor if you miss a dose. 

Dosage: The standard dosage is 300 mg, taken orally twice daily. 

Administration: It is advised to take the tablets approximately 12 hours apart. The tablets can be taken with or without food, but they should be swallowed whole and not chewed, crushed, or split.

Combination Therapy: Tucaxen is typically used in combination with trastuzumab and capecitabine until disease progression or unacceptable toxicity occurs.

Missed Dose: If a dose is missed, take the next scheduled dose at its usual time. Do not double up on doses. 

Warnings and Precautions of Tucaxen 150mg Tablets

Warnings and Precautions of Tucaxen 150mg Tablets

Here are the key warnings and precautions to be aware of when taking Tucaxen 150mg tablets: 

Risk of dehydration and other complications: Tucaxen can cause severe diarrhea, which can lead to dehydration, hypotension (low blood pressure), acute kidney injury, and even death. 

Monitor liver function: Tucaxen can affect your liver. Regular blood tests will be needed to monitor your liver function. 

Palmar-plantar erythrodysesthesia (PPED): Tucaxen can cause PPED, a condition characterized by redness, swelling, and pain in the palms of your hands and soles of your feet. 

Possible Side Effects of Tucaxen 150mg Tablets

Possible Side Effects of Tucaxen 150mg Tablets

Tucaxen, like many medications, can have side effects. While not everyone experiences them, it’s important to be aware of the potential side effects to help manage your treatment. 

Common Side Effects 

Digestive issues: Diarrhea, nausea, vomiting, and decreased appetite. 

 Fatigue: Feeling tired or exhausted. 

Headache: Pain or discomfort in the head. 

Skin reactions: Redness, swelling, and pain in the palms of your hands and soles of your feet (Palmar-plantar erythrodysesthesia or PPED). 

Serious Side Effects 

Severe diarrhea: This can lead to dehydration, hypotension (low blood pressure), acute kidney injury, and even death. 

Liver problems: Elevated liver enzymes. 

Serious allergic reactions: Hives, difficulty breathing, swelling of the face, lips, tongue, or throat. 

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