Glucantime 1.5g/5ml Injection (Meglumine Antimoniate)
₨5,000.00
Glucantime 1.5g/5ml injection contains meglumine antimoniate — a pentavalent antimonial compound manufactured by Sanofi and used worldwide as a first-line treatment for leishmaniasis. Online Pharmacy is one of the few reliable sources for genuine Sanofi Glucantime in Pakistan, supplying the authentic cold-chain product to patients and institutions across the country including in endemic regions such as Khyber Pakhtunkhwa, Balochistan, and rural Sindh.
Product Description
Brand: Glucantime
Packet Size: 5 ml ampoule
Strength: 1.5 grams per 5 milliliters
Form: Injection
Active ingredient: Meglumine antimoniate
Manufacturer: Sanofi
Treatment: Visceral leishmaniasis (Kala-azar)
✓ Medically reviewed by
Dr. Irfan Zia
Pharm.D · DRAP Reg. No. 1921245 · Reviewed March 2026
This product has been reviewed and approved by our DRAP-registered pharmacist for clinical accuracy. All medicines on onlinepharmacy.pk are authentic and sourced from licensed suppliers.
Additional Details
What is Glucantime used for? — Leishmaniasis treatment in Pakistan
Glucantime is used to treat leishmaniasis — a parasitic infection caused by protozoa of the Leishmania genus, transmitted to humans through the bite of infected female sandflies. Two forms of the disease occur in Pakistan:
- Cutaneous leishmaniasis (CL): The most common form in Pakistan, presenting as chronic skin lesions (painless, slow-healing ulcers or nodules) on exposed areas such as the face, arms, and legs. Most cases in Pakistan are caused by Leishmania tropica and Leishmania major. Cutaneous leishmaniasis is endemic in KPK, Balochistan, and FATA.
- Visceral leishmaniasis (kala azar): A more severe, systemic form affecting the liver, spleen, and bone marrow. Caused by Leishmania donovani. Presents with prolonged fever, weight loss, hepatosplenomegaly, and pancytopenia. Can be fatal if untreated.
Both forms require diagnosis and treatment under specialist supervision. A dermatologist (for cutaneous) or infectious disease specialist (for visceral) should confirm the diagnosis before treatment commences.
How Glucantime works
Meglumine antimoniate is taken up by macrophages — the immune cells in which Leishmania parasites reside. Inside the macrophage, the pentavalent antimony (Sb V) is reduced to the active trivalent form (Sb III) which disrupts the parasite’s energy metabolism, inhibiting fatty acid oxidation and glycolysis, ultimately killing the Leishmania organisms within the macrophage.
Dosage and administration
Important: Dosage and duration of Glucantime treatment are determined by the treating physician based on the type and severity of leishmaniasis. Do not self-administer this injection without medical supervision and training.
- Cutaneous leishmaniasis: Typically 20 mg/kg/day by IM or intralesional injection for 20 days
- Visceral leishmaniasis: Typically 20 mg/kg/day by IM or slow IV injection for 28 days
- Administered by intramuscular (IM) or slow intravenous (IV) injection under medical supervision
- Treatment duration and protocol determined by specialist based on response and tolerability
- Monitoring of cardiac function (ECG), renal function, and liver enzymes recommended during therapy
Side effects
Common: injection site pain, nausea, decreased appetite, abdominal discomfort, elevated liver enzymes, raised amylase/lipase. Serious: cardiac toxicity (QT prolongation — ECG monitoring required), pancreatitis, nephrotoxicity. All patients should be monitored by the treating physician throughout the course of treatment.
Storage and cold-chain
Storage: Store at 15–25°C away from direct sunlight. Do not freeze. Online Pharmacy maintains cold-chain packaging throughout delivery to preserve product quality.
Who should not take Glucantime?
- Patients with severe renal impairment
- Patients with severe hepatic impairment
- Patients with pre-existing cardiac arrhythmias or known QT prolongation
- Pregnancy — use only if benefit clearly outweighs risk, under specialist supervision
- Hypersensitivity to antimony compounds
Why source Glucantime from Online Pharmacy?
- Genuine Sanofi Glucantime — not a local substitute or compounded preparation
- Cold-chain delivery to all major cities and districts including Peshawar, Quetta, Karachi, Lahore, Islamabad, and Rawalpindi
- Prescription verified by DRAP-registered pharmacist before every order
- One of the most consistently available sources for Glucantime in Pakistan
- Free pharmacist consultation on storage, administration, and prescription requirements
Medical disclaimer: For educational purposes only. Leishmaniasis treatment must be supervised by a registered dermatologist or infectious disease specialist. Emergency: 1122.
Recommended Dosage of Glucantime 1.5g Injection
General Dosage: The standard dosage for adults and children is approximately 20 mg of pentavalent antimony per kilogram (kg) of body weight. This means that if you weigh, for example, 60 kg, your daily dose would be around 1200 mg of pentavalent antimony.
Gradual Increase: It is often recommended to start with a gradual increase in dosage. For the first three days, you might begin with one quarter, one half, and three quarters of the final dose, respectively. By the fourth day, you would then receive the full prescribed dose.
Maximum Dosage: Each 5 ml ampoule contains 1.5 g of Glucantime, which corresponds to approximately 425 mg of pentavalent antimony. Therefore, for every 20 kg of body weight, you might need between 1 to 3 ampoules per day, depending on your specific treatment plan.
Warnings and Precautions of Glucantime 1.5g Injection
Glucantime 1.5g injection is a potent medication that can cause significant side effects. It’s essential to be aware of the following warnings and precautions:
Cardiotoxicity: Glucantime can affect the heart, especially in individuals with pre-existing heart conditions. It can cause irregular heart rhythms, heart failure, and even sudden death in rare cases. Regular monitoring of heart function is crucial during treatment.
Electrolyte disturbances: Glucantime can lead to imbalances in electrolytes, such as potassium and sodium. These imbalances can cause serious health problems, including heart arrhythmias and muscle weakness. Your doctor will monitor your electrolyte levels closely.
Liver and kidney toxicity: Glucantime can damage the liver and kidneys. Liver function tests and kidney function tests will be performed regularly to monitor for any adverse effects.
Pancreatitis: In rare cases, Glucantime can cause pancreatitis, an inflammation of the pancreas. Symptoms of pancreatitis include severe abdominal pain, nausea, vomiting, and fever. If you experience these symptoms, seek medical attention immediately.
Hypersensitivity reactions: Some individuals may develop allergic reactions to Glucantime. These reactions can range from mild skin rashes to severe anaphylaxis. If you experience any signs of an allergic reaction, such as hives, swelling, or difficulty breathing, stop taking Glucantime and seek emergency medical help.
Pregnancy and breastfeeding: Glucantime should not be used during pregnancy unless the benefits outweigh the risks. It’s unknown if Glucantime passes into breast milk, so breastfeeding should be avoided during treatment.
Possible Side Effects of Glucantime 1.5g Injection
Glucantime can cause a variety of side effects, ranging from mild to severe. Some of the most common side effects include:
Mild side effects:
- Nausea and vomiting
- Loss of appetite
- Diarrhea
- Headache
- Fatigue
- Muscle aches and pains
- Joint pain
- Skin rash
- Fever
- Chills
Severe side effects:
- Heart problems, including irregular heart rhythms, heart failure, and sudden death
- Electrolyte disturbances, such as low potassium or sodium levels
- Liver damage
- Kidney damage
- Pancreatitis
- Allergic reactions, including hives, swelling, and difficulty breathing
Khalid Afridi –
My brother was prescribed Glucantime injections by his dermatologist following a diagnosis of cutaneous leishmaniasis. It was not available at pharmacies in Peshawar so we ordered online. Online Pharmacy had it in stock, product is original Sanofi, and cold-chain packaging arrived in good condition. Satisfied with the service.
Nazia Khattak –
Ordered Glucantime after prescription from an infectious disease specialist. Product arrived as original Sanofi with verifiable batch number and intact cold-chain packaging. The pharmacist confirmed storage and administration details before dispatch. Reliable service for a medicine that is not commonly stocked.
Jamal Khan –
Father was prescribed Glucantime by a specialist for visceral leishmaniasis. Online Pharmacy had it in stock and delivered to Quetta in 4 days. Product was sealed, authentic, and batch-verifiable. Four days to Balochistan is reasonable given the distance. Product quality was exactly as expected.
Bilal Zafar –
Ordered Glucantime for cutaneous leishmaniasis as prescribed by my dermatologist. The pharmacist called before processing to confirm the prescription and medicine details. Product arrived well-packaged with cold-chain intact. Good professional service for a specialist medicine that most pharmacies do not carry.
Dr. Shahzad Malik –
As a dermatologist I refer leishmaniasis patients to Online Pharmacy specifically for Glucantime. It is one of the few consistent retail sources in Pakistan. Product is genuine every time, prescription is properly verified, and the pharmacist understands the clinical context. Patient feedback has been consistently positive.