Casodex 50mg Tablets (Bicalutamide)

50,000.00

Casodex 50mg Tablets contains Bicalutamide which is now available in Pakistan at Online Pharmacy. The price range of the Casodex 50mg Tablets is Rs 7,000 to Rs 12,000/-. 

Product Description 

Brand: Casodex 
Form: Tablets 
Packet Size: 28 tablets 
Active ingredient: Bicalutamide 
Manufacturer: AstraZeneca 
Treatment: Prostate Cancer 

Category:
Additional Details

Additional Details

Uses of the Casodex 50mg Tablets

The uses of Casodex 50mg tablets (bicalutamide) are:

Treatment of Stage D2 metastatic carcinoma of the prostate (advanced prostate cancer that has spread to other parts of the body).

Used in combination with a luteinizing hormone-releasing hormone (LHRH) analog to block the effects of male hormones (androgens) that stimulate prostate cancer growth.

Sometimes used to reduce tumor flare when starting other hormone therapies for prostate cancer.

How Does Casodex 50mg Tablets Work?

Casodex 50mg (active ingredient: bicalutamide) works by blocking the action of androgens (male hormones like testosterone) in the body. It belongs to a class of medications called anti-androgens and is primarily used to treat prostate cancer.

Prostate cancer cells often need testosterone to grow. Casodex binds to androgen receptors in these cancer cells, preventing testosterone from stimulating their growth. By doing this, it slows down or stops the progression of prostate cancer.

How Should You Take Casodex 50mg Tablets?

It is important to take the tablet at the same time every day to maintain consistent levels in your body.

Swallow the tablet whole with a drink of water; do not crush or chew it.

Start taking Casodex at the same time as your luteinizing hormone-releasing hormone (LHRH) analog therapy, or at least 3 days before starting LHRH treatment or surgical castration.

If you miss a dose, skip the missed dose and take the next dose at the regular time. Do not take a double dose to make up for the missed one.

Continue taking Casodex regularly even if you feel well, unless your doctor advises otherwise. 

One 50 mg tablet taken once daily, either in the morning or evening, with or without food. Casodex should be taken at the same time each day. 

Warnings and Precautions of Casodex 50mg Tablets

Warnings and Precautions of Casodex 50mg Tablets

Liver toxicity:  
Severe hepatic injury and fatal hepatic failure have been reported. Liver function tests (serum transaminases) should be monitored before starting treatment, regularly during the first four months, and periodically thereafter. Use with caution in patients with liver impairment 
 
Allergic reactions:  
Uncommon but possible; symptoms include rash, itching, hives, swelling of face, lips, or tongue. Seek immediate medical attention if these occurNot for use in women or children:  
Casodex is contraindicated in women and children due to potential serious adverse effects. 
 
Use effective contraception:  
Men should use effective birth control during treatment and for 130 days after stopping Casodex, as it may harm an unborn child and impair fertility. 
 
Photosensitivity 
Casodex can increase sensitivity to sunlight, causing skin reactions. Patients should avoid excessive sun exposure and use protective clothing and sunscreen.  
Blood clotting:  
If taken with blood thinners (e.g., warfarin), close monitoring of blood clotting parameters (PT/INR) is necessary, as Casodex may increase bleeding risk.  
 
Heart conditions:  
Use caution if you have heart or blood vessel diseases, including arrhythmias, as Casodex may increase the risk of heart rhythm problems.  
 
Diabetes 
Casodex may reduce glucose tolerance; diabetic patients should monitor blood sugar levels closely and adjust treatment if needed.

Avoid abrupt discontinuation:  
Do not stop taking Casodex without consulting your doctor, even if you feel well.  

Possible Side Effects of Casodex 50mg Tablets

Possible Side Effects of Casodex 50mg Tablets

Possible side effects of Casodex 50mg tablets (bicalutamide) range from mild to serious and include:

Common side effects:

Hot flashes 

Breast pain, swelling, or enlargement 

Anemia (low red blood cells) causing tiredness or pale skin 

Fluid retention causing swelling in feet, ankles, legs, or arms 

Nausea, diarrhea, constipation 

Weakness, dizziness, fatigue 

Pain in back, pelvis, or stomach 

Increased urination, sometimes at night 

Blood in urine 

Shortness of breath or cough 

Infection symptoms like fever or chills 

Decreased sexual desire and impotence 

Serious side effects requiring immediate medical attention: 

Signs of allergic reactions: hives, swelling of face, lips, tongue, difficulty breathing. 

Liver problems: jaundice (yellowing of skin or eyes), dark urine, light-colored stools, upper stomach pain, loss of appetite, unusual tiredness. 

Sudden chest pain, wheezing, or difficulty breathing (possible lung inflammation). 

Unusual bruising or bleeding, especially if taking blood thinners. 

Severe allergic skin reactions or rash. 

High blood sugar symptoms: increased thirst, frequent urination, fruity breath odor. 

Other possible side effects: 

Hair thinning or changes in body hair 

Weight gain 

Depression or mood changes 

Indigestion or stomach discomfort 

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