Femara 2.5mg Tablet (Letrozole)
₨10,500.00
Femara contains Letrozole which is now available in Pakistan at Online Pharmacy. The price range of Femara 2.5mg Tablet in Pakistan is Rs.5,700/- to Rs 11,700/-.
Product Description
Brand: Femara
Packet Size: 30’s Tablet
Active ingredient: Letrozole
Manufacturer: Novartis
Treatment: Breast Cancer
Additional Details
Uses of the Femara 2.5mg Tablet
Femara 2.5mg tablets are primarily used to treat hormone receptor-positive breast cancer in postmenopausal women, to prevent cancer recurrence, and sometimes for fertility treatments.
Treatment of Hormone Receptor-Positive Breast Cancer:
If you have hormone receptor-positive breast cancer, Femara 2.5mg helps by lowering estrogen levels, which are known to fuel the growth of certain cancer cells. It is commonly prescribed to postmenopausal women to reduce the risk of the cancer coming back after surgery, radiation, or chemotherapy. By blocking estrogen, it helps stop the growth of these hormone-sensitive cancer cells.
Prevention of Cancer Recurrence:
After initial treatment, if you’re at high risk of cancer recurrence, Femara is often recommended as a preventive measure. It works by continuously suppressing estrogen production, thus lowering the chances of the cancer returning, particularly after the removal of tumors or following breast cancer surgery.
Fertility Treatment:
Femara is sometimes used off-label for fertility treatments, particularly in women who suffer from polycystic ovary syndrome (PCOS) or have difficulty ovulating. It works by stimulating the ovaries to produce eggs, making it a less risky alternative to other medications like Clomid. If you’re struggling with ovulation issues, Femara can help increase the chances of conception.
Post-Treatment to Reduce Recurrence Risk:
For women who have completed their breast cancer treatment, taking Femara for a few years can help lower the likelihood of cancer returning. This is especially useful in women who are postmenopausal and have estrogen-sensitive cancer cells.
How Does Femara Tablet Work?
Femara tablets work by blocking the enzyme aromatase, which is responsible for producing estrogen. This reduction in estrogen helps slow or stop the growth of hormone receptor-positive breast cancer cells, and can also aid in fertility treatments.
How Femara Tablet Works:
Blocking Aromatase Enzyme
Femara, also known as letrozole, works by inhibiting an enzyme called aromatase. In postmenopausal women, this enzyme converts androgens (male hormones) into estrogen. By blocking aromatase, Femara reduces the amount of estrogen produced in the body.
Reducing Estrogen Levels
Estrogen can fuel the growth of hormone receptor-positive breast cancer cells. By lowering estrogen levels, Femara helps prevent the stimulation of these cancer cells, reducing the likelihood of the cancer growing or spreading. This is particularly effective in women who are postmenopausal and no longer produce estrogen in the ovaries.
Slowing or Stopping Cancer Cell Growth
When the estrogen supply is cut off, hormone receptor-positive cancer cells, which rely on estrogen to grow, can no longer proliferate. This effect helps slow the progression of breast cancer and, in many cases, prevents its recurrence after surgery or radiation therapy.
Fertility Treatment Mechanism
In fertility treatments, Femara is used to promote ovulation. By reducing estrogen levels in the body, Femara tricks the brain into thinking estrogen levels are low, prompting the release of other hormones that stimulate the ovaries to produce eggs. This makes Femara a helpful treatment for women with infertility issues, such as those with polycystic ovary syndrome (PCOS).
How Should You Take Femara Tablet?
You should take Femara 2.5mg tablets once daily, as prescribed by your doctor, with or without food, and swallow the tablet whole with a glass of water.
Take Once Daily
Femara 2.5mg tablets are usually taken once a day. It’s important to take it consistently at the same time each day, as this helps maintain a steady level of the medication in your system.
With or Without Food
You can take Femara with or without food. There are no specific food restrictions, so you can choose to take it with meals or on an empty stomach, based on your personal preference.
Swallow the Tablet Whole
Take the tablet whole with a full glass of water. Avoid breaking, chewing, or crushing the tablet, as this may affect the way the medication works.
Missed Dose
If you forget to take a dose, take it as soon as you remember, unless it’s close to the time for your next dose. In that case, skip the missed dose and take your next one as scheduled. Do not double the dose to make up for a missed one.
Follow Doctor’s Instructions
Always follow your doctor’s instructions carefully. Femara is typically used as a long-term treatment, especially for hormone receptor-positive breast cancer, so it’s essential to stay on schedule and attend follow-up appointments for monitoring.
Recommended Dosage of Femara 2.5mg Tablet
The recommended dosage of Femara 2.5mg tablet is typically 2.5mg once daily, as prescribed by your doctor, with or without food, and for a period of 5 years for breast cancer treatment, or as directed for other conditions.
Standard Dose of 2.5mg Once Daily
The usual recommended dosage for Femara 2.5mg tablet is one tablet (2.5mg) taken once a day. This is the standard dose prescribed for hormone receptor-positive breast cancer in postmenopausal women. Your doctor may adjust the dosage based on your specific health condition.
Take the Tablet Consistently
It’s important to take the tablet at the same time each day to help you remember. This ensures that the medication works effectively, maintaining a steady level in your body. Femara can be taken with or without food, so it is convenient for your daily routine.
Follow Your Doctor’s Instructions
The duration of Femara treatment for breast cancer can typically last for 5 years, but this may vary based on your response to treatment. For fertility treatments, the duration and dosage may differ, and your doctor will guide you on how long to take the medication.
Do Not Alter the Dose
Never adjust the dose without consulting your doctor. If you miss a dose, take it as soon as you remember, unless it’s close to your next dose. In that case, skip the missed dose and continue with your regular schedule.
Warnings and Precautions
When taking Femara 2.5mg tablets, you should be aware of certain warnings and precautions. These include potential side effects like bone thinning, risk of cardiovascular events, and interactions with other medications. Always follow your doctor’s guidance closely.
Warnings and Precautions of Femara 2.5mg Tablets:
Bone Health Concerns
Femara can lower estrogen levels, which may lead to bone thinning or osteoporosis over time. If you are at risk for bone fractures, your doctor may monitor your bone health and may recommend supplements or treatments to protect your bones while on Femara. It’s essential to inform your doctor if you have a history of bone issues.
Cardiovascular Risk
Femara may slightly increase the risk of cardiovascular events, including heart disease or stroke, especially in individuals with pre-existing heart conditions. If you have a history of heart disease or risk factors such as high blood pressure or high cholesterol, discuss this with your doctor before starting treatment with Femara.
Pregnancy and Breastfeeding
Femara is not recommended for use during pregnancy, as it can harm the developing fetus. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is also advised not to breastfeed while taking Femara, as the medication may pass into breast milk.
Drug Interactions
Femara can interact with other medications, such as hormone replacement therapy or other cancer treatments. Ensure your doctor knows about all the medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, to avoid potential interactions.
Liver and Kidney Function
If you have liver or kidney problems, inform your healthcare provider. They may need to adjust the dosage or monitor your condition more closely during treatment.
Possible Side Effects of Femara Tablets
The possible side effects of Femara 2.5mg tablets include hot flashes, joint pain, fatigue, headaches, and bone thinning. Some rare side effects may also occur, so it’s important to monitor your health and report any concerns to your doctor.
Hot Flashes
One of the most common side effects of Femara is hot flashes. This occurs because of the drop in estrogen levels, which can cause sudden feelings of warmth, sweating, and redness, particularly in the face and chest. While uncomfortable, these are typically temporary and may improve over time.
Joint Pain and Stiffness
Some people experience joint pain or stiffness, especially in the knees, wrists, or hands. This can affect daily activities and mobility. If the pain becomes severe or persistent, your doctor may recommend treatments or modifications to manage this symptom.
Fatigue
Femara may cause tiredness or fatigue, which can make it difficult for you to carry out regular tasks or feel energized. It’s important to rest and manage your activity levels during this time. Let your doctor know if the fatigue becomes overwhelming.
Headaches
Headaches are another potential side effect of Femara. These can vary from mild to moderate in intensity. If you find the headaches unbearable or they interfere with your daily life, consult your doctor for advice.
Bone Thinning (Osteoporosis)
Long-term use of Femara can lead to bone thinning due to the reduction in estrogen levels. This increases the risk of fractures or bone pain. If you are at higher risk for osteoporosis, your doctor may monitor your bone health regularly and recommend supplements or other preventive measures.
Other Rare Side Effects
Although less common, some people may experience nausea, dizziness, mood changes, or liver issues. If you notice any unusual or severe symptoms, it’s important to contact your doctor immediately.
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