Aromasin 25mg Tablets (Exemestane)
₨12,000.00
Aromasin 25mg tablets contains Exemestane which is now available in Pakistan at Online Pharmacy. The price range of the Aromasin tablets is Rs 8,000/- to Rs 15,000/-.
Product Description
Brand: Aromasin
Form: Tablets
Packet Size: 15 Tablets
Active ingredient: Exemestane
Manufacturer: Pfizer
Treatment: Cancer
Additional Details
Uses of the Aromasin 25mg Tablets
Adjuvant Treatment of Early Breast Cancer
Used after surgery to reduce the risk of cancer recurrence in postmenopausal women with early-stage, hormone receptor-positive breast cancer.
Treatment of Advanced or Metastatic Breast Cancer
Prescribed when the cancer has spread beyond the breast and has not responded well to other hormonal therapies like tamoxifen.
Switch Therapy
Often used after 2–3 years of tamoxifen treatment, completing a total of 5 years of hormonal therapy to improve long-term outcomes.
How Does Aromasin 25mg Tablets Work?
Estrogen Fuels Certain Breast Cancers
Some types of breast cancer are estrogen receptor-positive (ER+), meaning they rely on estrogen to grow and spread.
Aromatase Enzyme Produces Estrogen
After menopause, the body produces most of its estrogen through the aromatase enzyme, which converts androgens into estrogen in fat and muscle tissue.
Exemestane Blocks Aromatase
Aromasin (Exemestane) irreversibly binds to aromatase, stopping the conversion process and significantly reducing estrogen levels in the body.
Lower Estrogen Slows Cancer Growth
With less estrogen available, the growth of hormone-dependent breast cancer cells is slowed or even stopped.
How Should You Take Aromasin 25mg Tablets?
Take it at the same time each day: This helps maintain a consistent level of the medication in your body.
Take it with food: Exemestane is better absorbed when taken after a meal. Avoid taking it on an empty stomach.
Do not crush or split the tablet: Swallow it whole with water unless instructed otherwise.
Follow the full course: Even if you feel well, do not stop taking Aromasin without your doctor’s approval. It’s often prescribed for several years in hormone therapy.
Missed a dose: Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up to make up for a missed tablet.
Recommended Dosage of Aromasin 25mg Tablets
The recommended dosage of Aromasin 25mg tablets for both early and advanced breast cancer in postmenopausal women is one 25 mg tablet taken once daily after a meal. This dosage is standard for adjuvant treatment following tamoxifen therapy and for advanced breast cancer when the disease has progressed after tamoxifen.
Warnings and Precautions of Aromasin 25mg Tablets
The key warnings and precautions for Aromasin 25mg tablets are:
Not for use in premenopausal women or those who have not yet gone through menopause, as it is only approved for postmenopausal women
Pregnancy and breastfeeding: Aromasin is unsafe during pregnancy and breastfeeding because it can harm the fetus or baby. Women who are pregnant, planning to become pregnant, or breastfeeding should avoid this medication and consult their doctor.
Bone health: Aromasin can cause bone loss (osteoporosis) and increase fracture risk due to reduced bone mineral density. Doctors typically monitor bone density and vitamin D levels during treatment and may recommend supplements to protect bone health.
Liver and kidney function: Patients with liver or kidney problems should inform their doctor before starting Aromasin. Liver or kidney impairment may affect drug metabolism and require dose adjustments or alternative treatments.
Allergic reactions: People allergic to exemestane or any ingredients in Aromasin should not take it. Signs of allergy include rash, swelling, or difficulty breathing and require immediate medical attention.
Driving and machinery: Aromasin may cause dizziness, weakness, or drowsiness. Patients should avoid driving or operating heavy machinery if these symptoms occur.
Do not stop treatment without medical advice: Even if feeling well, patients should continue Aromasin as prescribed to ensure effectiveness.
Avoid alcohol: Alcohol may increase drowsiness and dizziness when taken with Aromasin and should be avoided.
Possible Side Effects of Aromasin 25mg Tablets
The possible side effects of Aromasin 25mg tablets (exemestane) range from common mild symptoms to rare but serious reactions:
Common Side Effects
Hot flashes and sweating
Joint and muscle pain (arthralgia, musculoskeletal pain)
Headache and dizziness
Nausea, vomiting, diarrhea, constipation, and abdominal pain
Fatigue and tiredness
Insomnia (difficulty sleeping)
Depression, low mood, anxiety
Increased sweating
Loss of appetite or increased appetite
Swelling of hands, feet, or ankles (peripheral edema)
Bone thinning (osteoporosis) and increased risk of fractures
Hair thinning or hair loss
Skin rash or itching
Carpal tunnel syndrome and paresthesia (tingling sensations)
Less Common or Serious Side Effects (Require Medical Attention)
Signs of infection due to reduced white blood cell count (fever, chills, sore throat, cough)
Chest pain or tightness
Difficulty breathing or labored breathing
Severe allergic reactions (swelling of face, lips, tongue, throat; difficulty swallowing; rash; hives)
Confusion, dizziness, double vision, difficulty speaking or moving limbs
Yellowing of skin or eyes (jaundice), dark urine, clay-colored stools indicating liver issues
Unexplained broken bones or bone pain
Swelling of lymph nodes
Vomiting blood
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