What is a Xeljanz 5mg Tablets?

Xeljanz (tofacitinib) is a Janus kinase (JAK) inhibitor available in 5 mg immediate-release tablets and 11 mg and 22 mg extended-release tablets.

Can I Buy Xeljanz 5mg Tablets Online in Pakistan?

Yes, you can buy Xeljanz from Online Pharmacy, which is a reliable provider of wellness and imported medicines in Pakistan, offering 24/7 delivery service.

Can We Use Other Medicines with Xeljanz Tablets?

Xeljanz (tofacitinib) can interact with other medications, so it's important for you to inform your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Xeljanz and other medicines may affect each other, potentially causing side effects.

Can Alcohol Drinker Take Xeljanz 5mg Tablets?

While the manufacturer of Xeljanz, Pfizer, does not warn of an interaction between alcohol and Xeljanz, it is generally advised not to drink excessive amounts of alcohol while taking Xeljanz. This is because both alcohol and Xeljanz can affect the liver, and the risk may be higher if you take other immunosuppressants or medications that also affect the liver, such as methotrexate, or if you already have liver disease.

Does Xeljanz Tablets Affect Liver Patients?

Xeljanz (tofacitinib) can affect patients with liver issues. The medication has the potential to cause liver damage by altering enzyme levels, as shown in clinical trials. For patients with pre-existing liver conditions, close monitoring during Xeljanz treatment is essential. Symptoms of liver damage may include stomach pain, yellowing of the eyes or skin, and dark urine. If you experience any of these symptoms, it's important to inform your doctor. Liver function tests should be done before and during Xeljanz treatment to monitor liver function. It's crucial to discuss the potential risks and benefits of Xeljanz treatment with your healthcare provider, especially if you have underlying liver issues.

Does Xeljanz Tablets Affect Kidney Patients?

Xeljanz (tofacitinib) can affect patients with kidney conditions. The recommended dosage of Xeljanz should be reduced to 5 mg once daily in patients with severe renal impairment (creatinine clearance <30 mL/min). Xeljanz can also cause liver damage by altering its enzyme levels, as shown in clinical trials. For patients with pre-existing liver conditions, close monitoring during treatment with Xeljanz is essential. Symptoms of liver damage may include stomach pain, yellowing of the eyes or skin, and dark urine. It's important to discuss the potential risks and benefits of Xeljanz treatment with your healthcare provider, especially if you have underlying kidney or liver issues.

Can You Take Xeljanz Tablets if You’re Pregnant?

Xeljanz (tofacitinib) may affect the ability of females to get pregnant. It is not known if Xeljanz will harm an unborn baby. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Xeljanz during pregnancy.

Can I Take a Xeljanz Tablets Before Driving?

Xeljanz (tofacitinib) has no or limited effect on the ability to drive or use machines. However, it is always advisable to be cautious until you know how the medication specifically affects you. The medication is typically taken as a pill and is not expected to cause drowsiness or impair one's ability to drive. If you have any concerns about driving or operating machinery while taking Xeljanz, it is recommended to discuss them with your healthcare provider.

What is the minimum age for tofacitinib tablets?

Tofacitinib (Xeljanz) tablets are approved for use in adults aged 18 years and older for conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. For pediatric patients, tofacitinib is approved for children aged 2 years and older with active polyarticular course juvenile idiopathic arthritis (pcJIA), provided they have had an inadequate response or intolerance to one or more tumor necrosis factor (TNF) blockers.

What foods should I avoid with rituximab?

There are no specific foods you need to completely avoid while taking rituximab; however, it's advisable to avoid alcohol and excessive amounts of grapefruit or grapefruit juice, as they may interfere with the medication's effectiveness or cause adverse reactions. Always follow your doctor's dietary recommendations for optimal treatment outcomes.

Will I lose my hair with Xelijanz Tablets ?

Hair loss is not a common side effect of Xeljanz (tofacitinib) tablets. However, some individuals may experience mild hair thinning or shedding. If you notice significant hair loss while taking Xeljanz, it's important to discuss this with your doctor, as they may adjust your treatment plan or investigate other potential causes.

How many times can Xelijanz tablets be given?

Xeljanz (tofacitinib) tablets are typically taken twice daily for conditions like rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. For ulcerative colitis, the initial dose is 10 mg twice daily for 8 to 16 weeks, followed by a maintenance dose of 5 mg twice daily . Always follow your doctor's instructions regarding dosage and frequency.

How successful is Xelijanz Tablets?

Xeljanz (tofacitinib) tablets have demonstrated varying degrees of success across different conditions, with efficacy rates ranging from 35% to 60% for achieving clinical remission or significant improvement, depending on the disease and patient population.

Xeljanz 5mg Tablets (tofacitinib)

Q: Can You Take Xeljanz Tablets if You’re Pregnant?

Xeljanz (tofacitinib) may affect the ability of females to get pregnant. It is not known if Xeljanz will harm an unborn baby. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Xeljanz during pregnancy.

Q: Can I Take a Xeljanz Tablets Before Driving?

Xeljanz (tofacitinib) has no or limited effect on the ability to drive or use machines. However, it is always advisable to be cautious until you know how the medication specifically affects you. The medication is typically taken as a pill and is not expected to cause drowsiness or impair one's ability to drive. If you have any concerns about driving or operating machinery while taking Xeljanz, it is recommended to discuss them with your healthcare provider.

Q: What is the minimum age for tofacitinib tablets?

Tofacitinib (Xeljanz) tablets are approved for use in adults aged 18 years and older for conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. For pediatric patients, tofacitinib is approved for children aged 2 years and older with active polyarticular course juvenile idiopathic arthritis (pcJIA), provided they have had an inadequate response or intolerance to one or more tumor necrosis factor (TNF) blockers.

Q: What foods should I avoid with rituximab?

There are no specific foods you need to completely avoid while taking rituximab; however, it's advisable to avoid alcohol and excessive amounts of grapefruit or grapefruit juice, as they may interfere with the medication's effectiveness or cause adverse reactions. Always follow your doctor's dietary recommendations for optimal treatment outcomes.

₨40,000.00

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Xeljanz tablet contains (tofacitinib) which is now available in Pakistan at Online Pharmacy. The price range of Xeljanz 5mg Tablets is Rs 35,000/- to Rs. 45,000/-

Product Description:

Brand: Xeljanz
Packet Size: 56’s Tablets
Active ingredient: (Tofacitinib)
Manufacturer: Pfizer
Treatment: Arthritis

Category: Imported Medicines

Additional Details Of Xelijanz 5mg Tablets

Uses of Xeljanz 5mg Tablets

Xeljanz 5mg tablets are used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis. It works by inhibiting Janus kinase (JAK) enzymes to reduce inflammation and manage symptoms of these autoimmune diseases.

Rheumatoid Arthritis (RA):
Xeljanz 5mg is commonly prescribed to treat moderate to severe rheumatoid arthritis in adults who have not responded well to other treatments. It works by targeting and blocking JAK enzymes, which play a key role in the inflammation process that causes joint pain, swelling, and damage in RA.

Psoriatic Arthritis:
If you have psoriatic arthritis, a condition that causes joint pain and skin symptoms like psoriasis, Xeljanz can help reduce inflammation and improve both joint and skin symptoms. It helps by blocking the action of JAK enzymes, which are involved in the inflammation process.

Ulcerative Colitis:
Xeljanz is also prescribed for adults with moderate to severe ulcerative colitis, a chronic inflammatory bowel disease. By inhibiting JAK enzymes, Xeljanz reduces inflammation in the colon, helping to control symptoms like diarrhea, bleeding, and abdominal pain associated with this condition.

Ankylosing Spondylitis:
For ankylosing spondylitis, a type of arthritis that affects the spine, Xeljanz works by reducing inflammation in the spine and other joints, helping to alleviate pain and stiffness.

How Does Xeljanz 5mg Tablet Work?

Xeljanz 5mg tablet works by inhibiting Janus kinase (JAK) enzymes, which are involved in the immune system’s inflammatory response. By blocking these enzymes, Xeljanz reduces inflammation and helps manage symptoms of autoimmune diseases like rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis.

Inhibition of JAK Enzymes:
Xeljanz targets and blocks Janus kinase (JAK) enzymes, which are involved in the signaling pathways that trigger inflammation in the body. These enzymes play a role in immune cell activity, and by inhibiting them, Xeljanz helps reduce the abnormal immune response that leads to inflammation in autoimmune diseases.

Reduction of Inflammation:
By blocking JAK enzymes, Xeljanz disrupts the inflammatory process that contributes to conditions like rheumatoid arthritis and psoriatic arthritis. This helps to decrease the pain, swelling, and stiffness in your joints and prevents further joint damage.

Control of Immune System Response:
In conditions like ulcerative colitis and ankylosing spondylitis, Xeljanz works by reducing the immune system’s overactive response that causes inflammation in the colon or spine. This leads to fewer flare-ups and helps manage symptoms such as pain, bleeding, and difficulty moving.

Improvement in Symptoms:
By controlling the inflammation and immune response, Xeljanz helps improve the symptoms of various autoimmune conditions. This can lead to better mobility, fewer flare-ups, and improved overall quality of life.

How Should You Take Xeljanz 5mg Tablets?

You should take Xeljanz 5mg tablets once or twice daily, as prescribed by your doctor, with or without food. Always follow your doctor’s instructions for the correct dosage and schedule to manage your condition effectively.

Follow Doctor’s Instructions
The dosage of Xeljanz 5mg tablets depends on your specific condition and your doctor’s recommendation. Typically, you will take one tablet once or twice a day. Your doctor may adjust your dose based on your response to the medication.

With or Without Food
Xeljanz 5mg can be taken with or without food, as it does not require specific dietary restrictions. You can take it at a time that fits your schedule, but try to take it consistently at the same time each day for optimal results.

Swallow Whole
Take the tablet whole with a glass of water. Do not crush, chew, or split the tablet, as this may affect how the medication works.

Missed Dose
If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. In that case, skip the missed dose and take your next one at the usual time. Do not take two doses at once to make up for a missed dose.

Regular Monitoring
Because Xeljanz affects your immune system, your doctor will likely monitor your blood counts and liver function during treatment. Be sure to attend regular follow-up appointments and report any new symptoms or side effects.

Recommended Dosage of Xeljanz 5mg Tablets

For Rheumatoid Arthritis (RA):
The recommended dosage for adults with moderate to severe rheumatoid arthritis is 5mg twice a day. Your doctor may adjust the dose based on your response to the medication and any side effects you may experience.

For Psoriatic Arthritis:
For psoriatic arthritis, the typical starting dose is 5mg twice a day. Your doctor may modify the dose depending on how you respond to treatment.

For Ulcerative Colitis:
For moderate to severe ulcerative colitis, the recommended dose is 10mg twice a day for the first 8 weeks, followed by a maintenance dose of 5mg or 10mg once daily, depending on your doctor’s guidance.

For Ankylosing Spondylitis:
The recommended dosage is 5mg once a day. Your doctor may adjust the dosage based on your condition and how well you tolerate the medication.

Warnings and Precautions of Xeljanz 5mg Tablets

Xeljanz 5mg tablets have certain warnings and precautions. You should not take them if you have active infections, severe liver issues, or a history of certain cancers. Regular monitoring is required for blood counts, liver function, and the risk of serious infections.

Warnings and Precautions of Xeljanz 5mg Tablets:

Infections
Xeljanz can weaken your immune system, making you more susceptible to infections. If you have any active infections, including tuberculosis or hepatitis, inform your doctor. You may need to be treated for these conditions before starting Xeljanz. Your doctor will monitor you regularly for signs of infection during treatment.

Liver Issues
If you have severe liver disease or liver problems, Xeljanz may not be suitable for you. Your doctor will assess your liver function before prescribing the medication and may adjust the dosage if any issues arise. Regular liver function tests are important to ensure the medication is not harming your liver.

Cancer Risks
Xeljanz has been associated with an increased risk of certain cancers, such as lymphoma. If you have a history of cancer, especially blood cancers or lymphatic cancers, talk to your doctor before using Xeljanz. The medication may be contraindicated or require additional monitoring in such cases.

Heart-Related Concerns
Xeljanz can increase the risk of blood clots, heart attacks, or strokes, especially in people with pre-existing heart conditions. If you have a history of cardiovascular disease or blood clotting disorders, your doctor will monitor you closely while taking Xeljanz.

Blood Monitoring
Xeljanz can affect your blood cell counts, potentially leading to a low white blood cell count, red blood cell count, or platelet count. Regular blood tests are essential to check for any abnormalities, and your doctor may adjust the dosage or discontinue the medication if needed.

Vaccinations
Live vaccines should be avoided during treatment with Xeljanz, as the weakened immune system may not respond properly. You should get all necessary vaccines before starting treatment with Xeljanz. Discuss any vaccination needs with your doctor.

Side Effects of Xeljanz 5mg Tablets

The side effects of Xeljanz 5mg tablets may include infections, headache, elevated blood pressure, liver enzyme changes, and gastrointestinal issues. Rare but serious side effects can include blood clots, heart problems, and certain cancers.

Infections
Xeljanz weakens the immune system, increasing your risk of infections like respiratory infections, urinary tract infections, or shingles. You should contact your doctor immediately if you experience symptoms like fever, chills, or persistent cough.

Headache
Headaches are a common side effect of Xeljanz, especially during the early stages of treatment. These are usually mild to moderate and may subside over time. If the headache becomes severe, consult your doctor.

Elevated Blood Pressure
Xeljanz can cause a rise in blood pressure. It’s important for your doctor to monitor your blood pressure regularly during treatment, especially if you have a history of hypertension. You may need adjustments to your treatment plan if blood pressure rises significantly.

Liver Enzyme Changes
Xeljanz can affect liver function, leading to elevated liver enzymes. Your doctor will conduct regular blood tests to monitor your liver health, and the medication may need to be stopped if liver damage is detected.

Gastrointestinal Issues
Some individuals may experience gastrointestinal side effects like nausea, diarrhea, or abdominal pain. These symptoms usually improve over time, but if they persist, your doctor may adjust your treatment.

Blood Clots and Heart Issues
Xeljanz may increase the risk of blood clots, heart attacks, or strokes, especially in individuals with existing cardiovascular conditions. Symptoms such as chest pain, shortness of breath, or swelling in the legs should be reported to your doctor immediately.

Cancer Risk
There is a small risk of developing certain types of cancers, such as lymphoma or skin cancer, while taking Xeljanz. This risk is higher in individuals with a history of cancer or those who have long-term use of immunosuppressive medications.

Other Rare Side Effects
Rare but serious side effects may include liver problems, lung disease, or changes in blood cell counts. Your doctor will monitor you regularly to detect any potential issues early.

Reviews (2)

2 reviews for Xeljanz 5mg Tablets (tofacitinib)

Rated 5 out of 5

basit – May 13, 2024

Helpful custom service team and on time delivery service.
Rated 5 out of 5

Syed Asim – May 13, 2024

delivery was faster than expected.