If you have existing kidney problems or have had them in the past, it’s important to discuss this with your doctor before starting Humira treatment. Your doctor will likely keep an eye on your kidney function through regular blood tests while you’re receiving the treatment. If you notice any symptoms that might indicate kidney issues during your treatment with Humira, such as changes in your urination patterns, swelling in your legs or feet, or experiencing shortness of breath, it’s crucial to inform your doctor right away.