Yes, you can take a Centrum Lutein tablet before driving. It’s important, though, to be mindful of any side effects that could affect your driving ability. Centrum Lutein tablets are designed to help prevent or treat vitamin deficiencies, which might be due to a poor diet, certain health conditions, or pregnancy. Before you drive, we recommend ensuring you’re aware of how your body reacts to the supplement to keep both you and others safe on the road.