While Votrient (pazopanib) is not known to directly interact with alcohol, it’s important to be cautious. Drinking alcohol while taking Votrient could potentially worsen certain side effects, such as headaches, diarrhea, and nausea. Moreover, since Votrient can cause liver damage, consuming alcohol might increase the risk of further liver complications. It’s advisable to discuss your alcohol consumption with your healthcare provider to ensure your treatment remains as safe and effective as possible.